23. Avian leukosis
This refers to several leukaemia-like diseases caused by the avian leukosis virus (ALV). ALVs consist of 10 subgroups labelled from A to J, with 6 affecting chickens. A and B are the most common in chickens, especially egg laying hens, followed by J which occurs in broilers and egg layers. Subgroup E is oncogenic (causes tumours) and is widely present in domestic, non-commercial chickens. Hens are most commonly affected.
Lymphoid leukosis: This is the most common type of cancer caused by ALV in chickens. It occurs in chickens of 4 months or older. Tumours often develop in the liver, spleen and bursa of fabricius. Less commonly: Kidney, lung, gonad, mesentry and bone marrow. The bursa of fabricius is always involved.
Myeloid leukosis:
Caused by the subgroup j, it occurs in two, often overlapping, forms: myeloblastosis and myelocytomatosis. Myelocyomatosis causes multiple masses (myelocytomas) on the shanks, head, oral cavity, trachea and eye. They are often nodular and multiple, with a soft, friable consistency and of a cream colour. This mainly occurs in adults. The J subtype is genetically unstable.
Avian osteropetrosis
Transmission:
ALV is transmitted horizontally (from bird to bird by direct of indirect contact) or vertically (from infected hens to the offspring via their eggs). Most chicks are infected by contact with infected birds, which shed the virus in their faeces, saliva, scales and skin flakes. ALV has a short lifespan outside the bird.
Symptoms:
Loss of appetite; pale, shrivelled comb; enlarged abdomen; weakness; diarrhoea; weight loss.