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The good news is that the toxin in Oleander–a glycosoide called “oleandrin”–will deteriorate within about 50 days in an effective compost pile. Moreover, on tests conducted by UC Davis researchers, the toxin was not taken up by vegetables such as lettuce (which grow quickly) and tomatoes (which take longer to mature). The only possible danger the researchers noted could come from accidentally ingesting some not-fully deteriorated Oleander compost when harvesting leafy vegetables such as lettuce. Im mostly going to use the compost for compost tea for my trees and cactus and some in my garden but that wont be until next year by then it will be fully composted.I believe that Oleander leaves/branches contain a toxin that may not be beneficial in your compost pile.