Do not use insecticide spray. Locate where the ants are coming from and use something like
this close to the point of origin. When you use a spray (or drown them out, or pour boiling water on the nest), you actually encourage the ants to do something called budding as the colony feels threatened. Budding creates more ant colonies thereby increasing your problem. Using a bait like the link above (or you can create your own using borax and corn syrup if you are sure none of your animals/children will get into it) is the most effective way to rid yourself of a colony, as the ants take the bait back to the colony and kill the queens. If you are using baits, DO NOT SPRAY anywhere remotely close by. Any use of chemicals (insecticides, cleaners, fertilizers etc) near the bait will render it unattractive to the ants.
The above is mostly for the black ants. Fire ants are a completely different problem.
~former exterminator