Yes, we put Pandora down because we didn't want her to suffer any longer.Me too, it's no fun. I had an older dog treated, then went into remission. So when it came back, I had to set a boundary as to a dose of fluconazole that would compromise her quality of life (based on her prior treatment), and so the VF advanced through her spine. They either die/need euthanasia from the treatment, or from the disease itself.