Hello thailand,
I honestly believe, the discovery of the antibiotic is one of the most valuable medical discoveries of the 20th century, the modern anti-fungal "statins", is the second. Having said that, one must exercise great care in using them.
Antibiotics only work on bacteria, and certain bacteria require certain kinds of antibiotic. Fungus/yeasts also require the use of appropriate anti-fungal agents. Both antibiotics and anti-fungal medicines have been over used, thus creating resistance.
Here are the possible side effects of the medicines you want to use.
Itraconazole generally has a narrow margin of safety in
birds. Vomiting, loss of appetite and loss of weight have commonly been observed in treated
birds, however, these
adverse reactions are usually mild and dose related.
Itraconazole (Sporanox): an oral antifungal agent used in the treatment of aspergillosis, candida, Cryptococcus in psittacines; may cause hepatitis, bone toxicit, hypokalemia (a lack of potassium in the blood, usually caused by excessive amounts of it being excreted, that leads to muscle weakness, heart irregularities, disorientation, and sometimes cardiac arrest)
Enrofloxacin (Baytril): broad-spectrum antibiotic, useful for a wide variety of infections such as chlamydiosis; injectable, orally and in tablets; multiple injections should not be given—they can cause serious tissue, pain and nerve damage; it is bactericidal and has excellent activity against both Gram-positive and Gram-negative pathogens; this antibiotic has also been used to control certain intracellular pathogens; not well accepted by birds when put in drinking water.
The possibility of negative drug interaction exists. These are both potent drugs, you should
check with a Veterinarian before using them at the same time.
Since you decided to use the Itraconazole, you should use it for no more than 10 days. If the rooster displays any of the side effects mentioned above, discontinue use. If the infection is fungal there should be some improvement, a topical would be best, since the infection is in the eye and not in the crop. Give him a break from the antibiotics and give him some poultry probiotics to restore his good bacteria.
He has been on so many antibiotics already, It's my opinion that if the infection was bacterial, one of the antibiotic meds would have shown some improvement.
Besides encouraging resistant bacteria, over use of antibiotics will destroy the digestive ability of the rooster, by killing the good bacteria in the gut resulting in diarrhea. He will also be more prone to fungal infection of the skin, comb and wattles.
In stubborn cases like this, a veterinarian would take a tissue or mucous sample, and examine it under a microscope to identify the bacteria or fungus, then prescribe an appropriate medicine.
You can also try using Manuka Honey mixed with water that has been boiled then cooled. Use 50% honey and 50% water to make eye drops, use three times daily. If you don't have Manuka Honey available, use any honey, as long as it is a new jar. Honey is excellent at protecting tissue and antibacterial, anti-fungal, too. It has saved many chickens from horrible wounds.
I know you want him to get well fast, me too! There is a possibility he will lose sight in that eye. You are doing your best for him.
God Bless
