There is something to be said for outcross vigor. As a previous poster has said if you start noticing problems with productivity, fertility, size or vigor - weakness of any sort not just the mutants you are likely worried about, it's time to bring in a cross. The problem is that at that point it's not just troubles in the males it's also in the females.
Even if you just want a nice flock for general purposes rather than trying to develop something in particular - cull! It's far better to feed and care for a few good stock than a bunch of eaters that do not deliver (a pet or two excluded of course). Otherwise you are more likely to bring down the overall quality. Example, if you eat or sell off your best, you'll retain and breed lesser birds - then your flock will of course deteriorate.
If you are trying to "do" something - the advantage of line breeding related birds is you know better what they are likely bringing to the game both with dominant and recessive (hidden) genes and traits.
Even if you just want a nice flock for general purposes rather than trying to develop something in particular - cull! It's far better to feed and care for a few good stock than a bunch of eaters that do not deliver (a pet or two excluded of course). Otherwise you are more likely to bring down the overall quality. Example, if you eat or sell off your best, you'll retain and breed lesser birds - then your flock will of course deteriorate.
If you are trying to "do" something - the advantage of line breeding related birds is you know better what they are likely bringing to the game both with dominant and recessive (hidden) genes and traits.