Come Ramble With Me!

[CarpCharacin]

ipsc’s are an interesting topic with lots of potential but i would disagree with any of this research being conducted with stem cells from aborted fetal tissue vs the plethora of other options.

iPSCs are often seen as an alternative to embryonic stem cells, and some studies have even called the two indistinguishable. I don't think they're totally indistinguishable though. I've heard that iPSCs retain some DNA methylation that's characteristic of the cell types that they were derived from, but I don't think that nullifies their potential (though my opinions should obviously be taken with a large grain of salt since I'm not very well-read, lol). It's also possible to express the genes that are used to generate iPSCs within a living organism but stop before the cells lose their cell type and become iPSCs, and it really does seem to unlock at least some regenerative ability, however there's obviously the risk of going to far and I don't think it has as much potential as tissue replacement. Though the results seem similar to fetal wound healing ability.

 

[chickentrains]

@chickentrains come here

I said I'm on vacation and plus I don't come here anymore

 

[KingD]

iPSCs are often seen as an alternative to embryonic stem cells, and some studies have even called the two indistinguishable. I don't think they're totally indistinguishable though. I've heard that iPSCs retain some DNA methylation that's characteristic of the cell types that they were derived from, but I don't think that nullifies their potential (though my opinions should obviously be taken with a large grain of salt since I'm not very well-read, lol). It's also possible to express the genes that are used to generate iPSCs within a living organism but stop before the cells lose their cell type and become iPSCs, and it really does seem to unlock at least some regenerative ability, however there's obviously the risk of going to far and I don't think it has as much potential as tissue replacement. Though the results seem similar to fetal wound healing ability.

You talk like Alexa.

 

[CarpCharacin]

You talk like Alexa.

Hopefully It's mostly limited to when I'm talking about interests, but TBH I feel like I'm often not treated like a fellow human.

 

[KingD]

Hopefully It's mostly limited to when I'm talking about interests, but TBH I feel like I'm often not treated like a fellow human.

No, it's fine to lol!
I guess it's just your extensive knowledge.

 

[CarpCharacin]

No, it's fine to lol!
I guess it's just your extensive knowledge.

I don't think it's nearly as extensive as seems to appear.

 

[EmmaRainboe]

Congrats on starting your first hatch, sorry about the doa's

It's okay... I think I have one of each. I wanted to breed my rooster to the Ameraucanas. So it suck I don't have as many AMs as I had hoped, but I think I have one of each so I still can, and it gives more space for that. With the help of the genetics calculator I've worked out all the possible genotypes.

So, I plugged Feathers into the calculator and saw what I would get if I crossed him to Lavender and white Ameraucanas.

Possible offspring with lav mother. I hope I'm writing this right.

Male	E/E^R Co/co+ Lav+/lav S/s+ Pti/pti+ Mb/mb+ W/w+ Id/id+ O/o+ P/P	E/E^R Co/co+ Lav+/lav S/s+ Pti/pti+ Mb/mb+ W/w+ Id/id+ O/o+ P/p+	E/E^R Lav+/lav S/s+ Pti/pti+ Mb/mb+ W/w+ Id/id+ O/o+ P/P	E/E^R Lav+/lav S/s+ Pti/pti+ Mb/mb+ W/w+ Id/id+ O/o+ P/p+	E/e^b Co/co+ Lav+/lav S/s+ Pti/pti+ Mb/mb+ W/w+ Id/id+ O/o+ P/P	E/e^b Co/co+ Lav+/lav S/s+ Pti/pti+ Mb/mb+ W/w+ Id/id+ O/o+ P/p+	E/e^b Lav+/lav S/s+ Pti/pti+ Mb/mb+ W/w+ Id/id+ O/o+ P/p+	E/e^b Lav+/lav S/s+ Pti/pti+ Mb/mb+ W/w+ Id/id+ O/o+ P/P
Female	E/E^R Co/co+ Lav+/lav S/- Pti/pti+ Mb/mb+ W/w+ Id/- O/o+ P/P	E/E^R Co/co+ Lav+/lav S/- Pti/pti+ Mb/mb+ W/w+ Id/- O/o+ P/p+	E/E^R Lav+/lav S/- Pti/pti+ Mb/mb+ W/w+ Id/- O/o+ P/P	E/E^R Lav+/lav S/- Pti/pti+ Mb/mb+ W/w+ Id/- O/o+ P/p+	E/e^b Co/co+ Lav+/lav S/- Pti/pti+ Mb/mb+ W/w+ Id/- O/o+ P/P	E/e^b Co/co+ Lav+/lav S/- Pti/pti+ Mb/mb+ W/w+ Id/- O/o+ P/p+	E/e^b Lav+/lav S/- Pti/pti+ Mb/mb+ W/w+ Id/- O/o+ P/p+	E/e^b Lav+/lav S/- Pti/pti+ Mb/mb+ W/w+ Id/- O/o+ P/P

The white ones are a bit harder to figure out because recessive white hides other patterns. But I *believe* if they are from a high quality line a female should be E/E Ml/Ml c/c s+/- Mb/Mb O/O P/P. So assuming cackles female ameraucanas are as follows, Feathers crossed with one could yield these possible outcomes:

Male	E/E^R Co/co+ Ml/ml+ C+/c S/s+ Pti/pti+ Mb/mb+ W+/w Id/id+ O/o+ P/P	E/E^R Co/co+ Ml/ml+ C+/c S/s+ Pti/pti+ Mb/mb+ W+/w Id/id+ O/o+ P/p+	E/E^R Ml/ml+ C+/c S/s+ Pti/pti+ Mb/mb+ W+/w Id/id+ O/o+ P/P	E/E^R Ml/ml+ C+/c S/s+ Pti/pti+ Mb/mb+ W+/w Id/id+ O/o+ P/p+	E/e^b Co/co+ Ml/ml+ C+/c S/s+ Pti/pti+ Mb/mb+ W+/w Id/id+ O/o+ P/P	E/e^b Co/co+ Ml/ml+ C+/c S/s+ Pti/pti+ Mb/mb+ W+/w Id/id+ O/o+ P/p+	E/e^b Ml/ml+ C+/c S/s+ Pti/pti+ Mb/mb+ W+/w Id/id+ O/o+ P/P	E/e^b Ml/ml+ C+/c S/s+ Pti/pti+ Mb/mb+ W+/w Id/id+ O/o+ P/p+
Female	E/E^R Co/co+ Ml/ml+ C+/c S/- Pti/pti+ Mb/mb+ W+/w Id/- O/o+ P/P	E/E^R Co/co+ Ml/ml+ C+/c S/- Pti/pti+ Mb/mb+ W+/w Id/- O/o+ P/p+	E/E^R Ml/ml+ C+/c S/- Pti/pti+ Mb/mb+ W+/w Id/- O/o+ P/P	E/E^R Ml/ml+ C+/c S/- Pti/pti+ Mb/mb+ W+/w Id/- O/o+ P/p+	E/e^b Co/co+ Ml/ml+ C+/c S/- Pti/pti+ Mb/mb+ W+/w Id/- O/o+ P/P	E/e^b Co/co+ Ml/ml+ C+/c S/- Pti/pti+ Mb/mb+ W+/w Id/- O/o+ P/p+	E/e^b Ml/ml+ C+/c S/- Pti/pti+ Mb/mb+ W+/w Id/- O/o+ P/P	E/e^b Ml/ml+ C+/c S/- Pti/pti+ Mb/mb+ W+/w Id/- O/o+ P/p+

 

[DucksAreBest]

What are y'alls dream animals?

 

[EmmaRainboe]

What are y'alls dream animals?

Peafowl.

 

[EmmaRainboe]

Peafowl.

And Nigerian Dwarf Goats.