Yes, I know Lupus is a mystery disease with many suspected causes. Some male athletes have this disease. It is a disease of the immune system and does have many different symptoms. My wife has rheumatoid arthritis as a result of this disease. She had to retire early because stress seems to stir up Lupus. She gets the "butterfly rash" when she is having a Lupus attack. For those that don't know, that is a reddening of the skin of both cheeks and nose on her face. She has lived with this disease for 20 years. You have my deepest sympathy.I was the one diagnosed. I do not drink or eat anything diet. I am a herbalist and very aware of the chemical nonsense they put into processed foods. Lupus is a mystery disease. Some think it to be genetic and some think it is caused by lifestyle choices and our environments. Some just dont claim to have an answer. What they all can agree on however, is that patients suffer great deals of pain and fatigue, memory loss, kidney problems(most not all) skin rashes, depression, and you are in constant danger of heart attack or stroke, kidney disease or failure, or any other organ diseases or major complication as your body attacks and destroys any and all healthy tissue. Some people are diagnosed with a slow or less complicated form others are diagnosed with the hard or severe form as I was. Lots of things will continue to effect my body and cause flare ups to arise or worsen,such as your aspartame and anything artificial or processed. There are so many lifestyle changes that are to be made. The disease is life threatening and depending upon the severity and how many changes you make after you are diagnosed there really is no telling how any particular person will react as far as organ and tissue health.