CosBac: A Multi-Species Probiotics Combination along with Prebiotics as a Poultry Feed Additive for Total Gut Health Solution

Pravin

Hatching
Oct 25, 2020
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Need of Probiotics in Poultry Feed

  • Efficient commercial poultry production is a combined act of nutrition, gut health, and animal welfare, especially when reducing or eliminating antibiotic utilization.
  • Different types of challenges such as diseases, environment, and feed ingredient types, can negatively impact the intestinal microbial balance in poultry, leading to slower growth and reduced performance.
  • Overgrowth of pathogenic strains of Clostridium perfringens can result in different disorders such as diarrhoea, necrotic enteritis, gangrenous dermatitis, and focal duodenal necrosis, can ultimately impair feed efficiency, growth and wellbeing of the birds. This can cause economic losses for poultry producers.

Importance of Healthy Gut in Commercial Poultry Production


  • The gastrointestinal (GI) tract of chicken harbour a diverse and complex microbiota that plays a vital role in digestion and absorption of nutrients, immune system development and pathogen exclusion.
  • Healthy gut is a foundation for optimum bird performance and the integrity, functionality and health of the chicken gut depends on many factors including the environment, feed and the gut microbiota.
  • If the gut health & its functions are impaired then digestion and absorption of nutrients are affected thereby health and performance of the birds will be compromised.
  • Improper digestion of nutrients in the upper part of gut leads to undesirable shifts in the lower part of gut microbiota which have shown negative impact on bird performance.
  • Thus, healthy gut is of prime importance in order to achieve production goals along with feed cost savings and to maintain environmental sustainability. To maintain healthy gut environment and improve production performance probiotics are added as a poultry feed additive.
About CosBac

CosBac is a poultry-specific, multi-species synbiotic poultry feed additive that promotes eubiosis, enhances immunity, reduces rate of chick morbidity and mortality thus maximising economic return. CosBac offers Integrity, Protection and Balance by taking care of chicken gut health. It comprises endospores of unique non-GMO strains that grows profoundly in the gut of monogastric animals that survives high pelletization temperature and unfavourable gut conditions. CosBac is available in both feed and water-soluble forms.

CosBac Composition

CosBac is a multispecies synbiotic comprising Bacillus subtilis (PLSSC) 5x109 CFU/g, Bacillus coagulans (LBSC) 3x109 CFU/g and Lactobacillus acidophilus 2x109 CFU/g with guaranteed total potency of ≥ 10x109 CFU/g along with prebiotics.

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Mechanism of Action

  • Contains a combination of aerobes and facultative anaerobes selected for their effectiveness to thrive and proliferate in the high and low-oxygen environment across the entire gut.
  • Prevents adherence of the pathogenic bacteria to host cells by strengthening the barrier effect of the intestinal mucosa and by release of gut-protective metabolites (arginine, glutamine, short-chain fatty acids and conjugated linoleic acids).
  • Produces short chain fatty acids (SCFA) such as lactic acid, and bacteriocins like coagulin, amicoumacin, and subtilisin.
  • Enhances the activity of digestive enzymes such as amylase, protease and lipase which help in digestion of complex molecules in feed, ensuring increased energy conversion.
  • Improves the humoral immune response by increasing antibody production and produces a variety of cytokines and lymphokines.

Role of CosBac in Alleviating the Negative Impact of Summer Stress on Bird Performance


Heat stress is known to impair the performance, productivity and health of the birds by reducing feed intake, decreasing nutrient utilization, disrupting intestinal structure and compromising the immune system. Heat stress has been shown to impair the intestinal morphology and barrier integrity of chickens leading to impaired digestive and absorptive capacity and increased permeability to luminal antigens and toxins. It is well known fact that heat stress adversely changes the metabolic status and physiological equilibrium in birds leading to health problems and high mortality rate.

Besides improving environmental management, nutritional strategies in terms of probiotics supplementation as a poultry feed additive are important to partially alleviate the negative impact of heat stress on birds. Among the poultry feed additives, probiotics have gained more attention from poultry nutritionists as these are capable of improving the physiological conditions, intestinal morphology and structure, immune system and thus performance and well-being of heat-stressed birds.

CosBac to Protect Newly Hatched Chicks

Under normal conditions (i.e. in the wild), animals pick up their microflora from adult animals and from the environment very quickly, but under conditions of modern poultry production, things are different. Commercial broiler chickens are hatched in extremely clean conditions and don’t have contact with adult animals. Then they are transferred in houses previously cleaned and disinfected. For them, to build up and establish a well-balanced microflora is difficult. During that time, the chicks are not protected against the colonization with pathogenic microbes. For the chicks, it is crucial to develop a protecting microflora as early and fast as possible, which can be supported by the application of probiotics in poultry feed.

CosBac and Necrotic enteritis

Necrotic enteritis is one of the world’s most common and financially crippling poultry disease, which when triggered can cause mortality rates of up to 50%. Various research groups have investigated the use of a multi-species probiotic combinations may be beneficial in the control of poultry diseases, which are related to Clostridium perfringens. In conclusion, the data of these studies suggest that the multi-species probiotics are able to control poultry diseases like Necrotic enteritis and Gangrenous dermatitis. The use of probiotics in poultry feed can provide the poultry industry with an alternative management tool that has the potential to promote better intestinal health by managing the composition of the microbial population in the GI tract, to protect poultry flocks from infections with pathogenic bacteria and to decrease monetary losses due to pathogens.

Advantages of CosBac
  • Promotes optimal development of gut microbiota especially post-hatch.
  • Production of short chain fatty acids (SCFA) and metabolites with proven activity against C. perfringens, E.coli and S. enteritidis.
  • Builds up immunity against pathogens in early chick stage and mitigates infection risks including necrotic enteritis (NE).
  • Re-establishes balanced gut microflora during post-antibiotic application.
  • Reduces incidence of wet litter and pasty vent.
  • Effectively reduces early chick morbidity and mortality.
  • Zero withdrawal period and can be administered throughout the life cycle of animals.
Product Specification

Recommended Inclusion Levels:

CosBac (Feed)


For Broiler: Pre-starter & starter: 200 g/ton of feed

Finisher: 100 g/ton of feed

For Layer/Breeder: 100 g/ton of feed

CosBac (WS)

Continuous Application: 2 g/1000 birds/day

Intermittent Application: 20 g/1000 birds/day

Presentation:

CosBac (Feed):
Available in 25 kg HDPE drum and 20 kg (5x4) pack size

CosBac (WS): Available in 500g & 200g pack size in bottle

Physical Appearance: Free flowing powder
 

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