I have sand runs and also sand in my coops. I clean the poop out of the sand regularly with a metal cat box scooper.
If you are asking about changing the sand from old and used to new, it's an arduous process, and after several years of having the same sand in my run, I did shovel it all out and put in new, clean sand. The reason I did this was because it had become unbearably dusty due to my having mixed decomposed sandstone with construction sand over a loose clay soil.
If you put in sand over a non-dusty soil, you probably won't have the problems I had. Now I just keep adding to the sand in coop and run and it stays relatively clean and non-dusty.
The thing I love about sand is it's so easy to keep the poop picked up, and the chickens love it for dirt bathing and digging. It also acts as a heat sink in winter, adding warmth, and in summer, I can wet it down and achieve an evaporation effect. The chickens like to hunker down in the cool damp sand to cool off. If your climate is extremely humid, though, this might not work to your advantage to wet it down. But it still makes a great bedding for the chickens.