Diary & Notes ~ Air Cell Detatched SHIPPED Chicken Eggs for incubation and hatching

[casportpony]

Hi all.

I have been busy in my real world. I have passed by but the thread has been quiet.

There is not a lot of data on the tetragenic effects of off label wormers in poultry

I have hatched eggs after ivermectin without any issues.

Valbazen definitely has issues with ruminates during first trimester.

Safeguard can be given to ruminates safely.

The warnings about aplastic anemia are what keep me from using Valbazen.

-Kathy

 

[ozexpat]

Digging deeper on Albendazole (Valbazen)

from: https://s3.amazonaws.com/compliance...ns/15822_0b6251268435c427862c9b9c52caafa5.pdf

note the embryo toxicity occurred in rodents when given at high doses for many days

REPEAT DOSE TOXICITY DATA
SUBCHRONIC / CHRONIC TOXICITY:
Albendazole was given to beagle dogs (6 male and 6 female) at dosage levels of 0, 5, 30, and 60 mg/kg bw/day for six months. A decrease in food
intake was observed in the 30 and 60 mg/kg dosed females, and weight gain was decreased in the 60 mg/kg dosed males and females. Decreased
absolute and relative testes and uterine weights and slight increases in relative liver and kidney weights were observed in the 60 mg/kg dose group. An
incidence of small nodules in the stomach were increased in all treated groups, but they were shown to be normal submucosal lymphoid follicles
microscopically. Hypocellularity was observed in the sternal bone marrow in the 60 mg/kg dosed group. The No Observed Effect Level (NOEL) was 5
mg/kg bw/day.
REPRODUCTIVE / DEVELOPMENTAL TOXICITY:
Albendazole has caused embryotoxicity and skeletal malformations in pregnant rats and rabbits. Fetal effects observed in rats occurred at 10 to 30
mg/kg/day administered during gestation days 6 to 15. Rabbit teratogenicity and maternal toxicity was observed at 30 mg/kg/day administered during
days 7 to 19. No teratogenic effects were observed in mice given oral dosages up to 30 mg/kg/day administered during gestation days 6-15. No effects
on male or female fertility were observed in rats given oral dosages of 30 mg/kg/day. Albendazole has been shown to be excreted in animal milk. Its
presence in human milk has not been determined.
Reproductive effects of albendazole were investigated in multigeneration oral-dosing studies in rats. Albendazole caused reduced survival and growth
rate during the post-natal lactation period. The NOEL was 5.8 mg/kg bw/day.
MUTAGENICITY / GENOTOXICITY:
Albendazole was negative in an Ames study, a chromosomal aberration test, metaphase analysis assay in Chinese hamster ovary (CHO) cells, and in a
mouse micronucleus test. Albendazole induced weak activity in an in-vitro BALB/3T3 cells transformation assay in the presence of metabolic activation
only. Albendazole isolated from a formulated product gave a positive result in an in vivo mouse bone marrow micronucleus test. Future Phrase
CARCINOGENICITY:
Albendazole was not carcinogenic in rats or mice administered 20 mg/kg/day for 117 weeks or 400 mg/kg/day for 108 weeks, respectively.





In the Philippines, Valbazen is cheap ($20/Liter) versus $75 in USA. I use it twice a year as I routinely dose all my animals at once 4x per year for paracites, alternating with Ivermectin.

Anecdotally, in doses of 10mg/kg I have had no issues with egg production or their hatchability. I have not performed randomized trials against a control

 

[ozexpat]

The warnings about aplastic anemia are what keep me from using Valbazen.

-Kathy

The risk of aplastic anemia is low. Like any drug you or your animals take, you have to evaluate risk versus benefit.

 

[Sally Sunshine]

Avian mycoplasmosis in Asia
Procedures for the establishment of mycoplasma-free breeding flocks

I forget who it was that was dealing with mycroplasmas and had posted about breeding for stronger flocks, this was a link on FB I found not too long ago, I will throw it here so I dont forget.






And this was a new bookmark I added to those who are thinking about vacinations

Yolk retention and yolk sac infection is considered as an important cause of death in chicken as well as
in guinea fowl, duck, turkey, quail and goose.

 

[Sally Sunshine]

I dont have kids for four days UNplanned and I already dont know what to do with myself! Its like a back to school teaser!

 

[DaveOmak]

I dont have kids for four days UNplanned and I already dont know what to do with myself! Its like a back to school teaser!

OH MY !!!!!!!

 

[Sally Sunshine]

Quote: well I have my own just not anyone else s LOL

 

[sumi]

Sally... This is the current pageviews on your Hatching 101 article: 99,984 views. It should hit 100K before the day's out.

You've helped a lot of people, girl!

 

[Sally Sunshine]

Sally... This is the current pageviews on your Hatching 101 article: 99,984 views. It should hit 100K before the day's out.

You've helped a lot of people, girl!

 

[Sally Sunshine]

I have been trying to keep up with the links to be sure they are all working yet, but for some reason I opening it it runs and runs, I think its too long for my crappy service to open up fully! I reset my modem a zillion times, but still get errors, even on threads its giving me crap! I am not sure why byc give me such computer issues, I know its my server but there must be alot of something that needs to run for it to take forever to open, oh well, the hughsnet ppl told me to purchase an outlet timer and shut everything down each evening and have it boot up before I get up, I keep forgetting to get one at the store. they say that something with electric makes it malfunction after awhile static or something, and that reboot from my laptop wont work. I will figure it out later today, I was on the phone last night for an hour with them yet again because of having so much issues the past few days! arggg