From researching the cost online I found that the most inexpensive price was $30 for a vial with dilutant that would inoculate 1000 chicks There is also the cost to ship it which is an additional $20. The syringes and needles are not included, and while they are inexpensive, you should count that cost as well. The shelf live for the mixed vaccination solution is one hour. Since it is impossible to inoculate even close to 1000 chicks in one hour, the majority of the solution is wasted. I don't know why the pharmaceutical company would even sell it this way as it is really false advertising. If you have an incubator full of eggs, some of them are bound to hatch later than others, meaning that you would have to buy more than one bottle of vaccine, doubling and perhaps even tripling the cost Because Marek's is virulent in places like the Pacific Northwest, I believe that this sort of thing should be regulated by the Department of Agriculture. If there were regulations regarding the cost of the vaccine the disease might be controlled so it is more manageable for people who are trying to be self sufficient by producing they own food As it is now, the way the vaccine is being distributed favors the poultry industry and not backyard farmers. Not everyone can order the minimum numbers required by online hatcheries that offer vaccines for day old chicks so we are forced to buy the vaccine ourselves and vaccinate chicks that we hatch ourselves Likewise, most chicks that are offered for purchase on places like Craigslist are not vaccinated.