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They can go down hill pretty fast if a vet is an option especially if this has been going on for a while, tube feeding would be an option and antibiotics if there is an infection present is your duck male or female @Foxy10

So sorry for you lossI had a sick muscovy hen go without food for a while, I want to say around 2 or 3 weeks without eating before she died. I am not sure why she went off food and at the time I did not know about this site. I just tried googling stuff and asking people. I never found an answer.
Have you learned how to tube feed yet?I will look at it, thank you!So sorry for you lossHave you learned how to tube feed yet?
This thread shows how successful tube feeding can be:
https://www.backyardchickens.com/threads/help-ducks-attacked-by-mink.1294178/
It's a long thread, but very educational.