Some, yes. It never gets any easier.
We've raised hundreds over the years. I've been having trouble counting back, we switched breeds a lot.
The two biggest factors for us have been genetics and cocci.
Genetics can cause some individual chicks to just not thrive, they eat but don't grow very fast, if at all, and eventually get weak and die. I think it has something to do with the way their gut is formed, just a guess. It doesn't seem more connected to one breed than another.
Nature presents series of tests for survival, and some just don't pass. I still try to help them and cry when they go.
With cocci, the longer you have birds on the land, the higher the burden of cocci, just about everywhere. I medicate the water instead of feed, but at times I've gotten too confident in their resilience.
There are many strains, some are much meaner than others.
Other causes:
I lost one chick when it was sleeping on a baby roost, 6 inches off the brooder floor. The chick next to him jostled him, he fell to the side and banged his head on the wall, then flopped and died quickly (broken neck).
On another occasion, we lost a half grown juvenile in a similar manner out in the coop.
A few Faverolles chicks passed from shipping stress.
One chick got something like vent gleet, even though she was too young for it. I haven't seen it before or since. I think something was up with the way her innards were formed, or perhaps she ate something she shouldn't have. It's a mystery.
A beautiful young pullet was eaten by a rat(!!!) at night, when her 3-month-old flock was still insisting on sleeping on the floor of the coop. Dang rat got through a very small gap, I was so upset!
Ever since, I force juveniles to roost whether they want to or not, by timing it so I'm picking them up there right before it's too dark for them to move.
For all the pain, we've still had a lot of success. I'd say 95-98% have made it. Good thing too, hatching chicks is something I do because it reminds me of the blessing that is life.