I have a coop with a people door and a side chicken door that goes into their run. I will go out at first light before the chickens are off their roosts. If you have help, it makes it easier. Grab a chicken off the roost, take it out the people door to my waiting helper. Wrap the chicken up in a towel so the holder doesn't get scratched and the chicken is calmer. The other person puts a pea size dollop of safeguard (I have larger birds, so I used just slightly more) on a finger. Then either the holder or the other one opens the chicken's mouth and puts the safeguard on the chicken's tongue. I usually hold the beak shut for a second to make sure it goes down. Then just release the medicated chicken into the run. Repeat for all the birds. When done, open up the chicken door into the run, and you are done. If you do it this way, you won't get confused which birds are already done, and which still need to be done.