No. I open my bator frequently during hatch. As long as your humidity stays up and comes up good once you close, it should be fine. I would be worried about the one who is giving off the order though. It could contaminate the others.I have an external pip! One. Opened the bator to find the "smell". Still haven't localized it. Bumped one egg, and panicked....when I saw pip. Bator only cracked a hands width. I was making sure no more had seeped and were "stuck" (like one had been). Don't suppose I hurt the pipped egg, do you? It isn't peeping though...not that I've heard. Just watching. Day 23 1/2. There is at least one bad egg! It's why I opened the bator up. It stinks to high heaven, and I'm not finding it just "looking" at them.