Talking to a vet from A & M, he told me that the incidence of it passing through the egg if it's micoplasmosis drops after a few years. Don't know how true that is? But a swollen sinus doesn't mean that is what it is. I have had a few birds with swollen sinus, I didn't remove them from the flock, just treated where they were. In those cases (all three times in 15 years), it was just one bird with a swollen sinus and none of the others had problems. In two cases, I completely depopulated a year or two later, so none were related. Case number three is when I got a pair of peachicks in the fall of '08. Shortly after I got them, one had a sinus problem. I contacted the seller who verified that their birds had it, too. She offered to buy the birds back, but I declined. I treated the sick pea with Tylan, the other pea never showed symptoms. Even though the past two winters were harsh (colder then average, temps down to -38F, some days with a high of -20F) and I am sure that caused them some stress, they are both still doing fine and had no more problems. Summer of '09, I got some turkeys. I don't disinfect my boots when I go from one pen to the other, but none of my turkeys had any sinus issues either. So if by 'hands on experence with this nasty disease' you mean swollen sinus in general, that is my experience. If you are referring to experience with micoplasmosis, without testing we can't say that is what this turkey has. It may just be a cold. Though for all I know, mine may have it and I just don't know it. If that is the case, it doesn't appear to be hurting them.