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I can't pick most of mine up when they are out and about, either. Usually, though, chickens are much tamer when on the roost. I have handled every one of them several times by going in the coop at night and picking them up one by one. I've done it to worm them and check for lice/mites, etc.
Lice/motes are carried by wild birds. They can get them from wild birds simply flying over the chickens, and an infestation can actually kill a chicken if it gets bad enough. So I check them every now and then. Two of mine will let me pet them and eat from my hand, and some others can be handled when on the nest. I'll check one when I happen to be able to catch her, and I check everyone every few months.
I have read on here, "If you have chickens, you have lice or mites," though I've never seen any. But they get Eprinex for worms once a year, which also kills lice and mites. And I spray or dust with pyrethrin/permethrin in the coop.