BJ is right. Try the VetRX first. Rub it full strength on their head and under the wings. Read the directions that come with the box. It will tell you how to use a cotton swab for the sinus and eyes. VetRX does not mix with cold water but will mix with WARM water. You can put a little on a small drinking container of cold water for 2 to five days and when they dip their beaks to drink, it will be in their nose and throat, medicating them . If that don't fix them, you can get Lincomycin or several other respitory antibiotics and give them intramuscular shots for 5 days (YES, you CAN give your chickens a shot!) No sense in getting anxious yet. If that don't work, message me and there are several options before culling. Chickens sometimes show the signs yours have when they get cold and wet, anxious, stressed or have a flare-up of CRD, which 90% of all chickens have. Yours have what we know as "respitory stress". Chickens don't get colds but they DO get something very simular to it.