Depend are where you are...I am on well so no issues...but when I lived in town I let the water set for 3 days and the chlorine levels will go down to nothing naturally. I quit using any conditioners in the water because (well...this is me only speaking of) had issues with to much slime coat...it can hurt them too. Start right is ok (turn the water blue if I remember correctly) but I always used less than it called for. "Prime" I believe it is called is the only one I would use towards the end of my breeding days...it was great but smelled like sulfur...lol A good test kit is always awesome to have on hand for when you are in doubt...and pH and ammonia levels are great to track too if you want to get that precise.