I am confident in how I am dealing with chronic mycolplasma in my younger chickens and the flock overall isn't affected by more than 10% of them getting sick (of 50 birds). It only effects my younger ones, as the older ones that had it have only get mild recurring symptoms and havent needed treatment.
First importance is keeping watch on their leaking eye in the morning, and keeping their face and eye clear of the mucous discharge. During a severe outbreak, I clean their face every morning to keep the mucous from building up causing blisters, infections, etc. Even during an outbreak, sometimes I let it go a couple of days before it needs cleaned for them. So excessive mucous needs to be kept clean.
As for antibiotics, I have a special mixture they get, so I will assume you don't have the same medicines. But I only give the antibiotics the same day of the face cleaning, if it is a severe outbreak. That is partly because I can't treat 5 minor cases every day, I only can do one or two that have mucous build ups on their face. They get antibiitics only one day, sometimes two days on a row. I never keep giving antibiotics every day, only during an outbreak and the medocine does seem to reduce the severity of the outbreak. So only give antibiotics one or two days, folkowed by monitoring the symptoms. Often time a couple of these abtiviotcs and treatments they will grow out of the symptoms and they go away for weeks or forever. Lots of my chickens only got a one or two day treatment, and symptoms went away and they are now adults with no symptoms.
The biggest thing is hygiene of theor eyes and face. Cleaning the mucous during their initial major outbreaks. Yesterday I did antibiotic treatments for two, and cleaned their faces. Today I have none to treat, and tomorrow too. Lidocaine eyedrops also help after the face cleanings, I apply eyedrops and then dry their faces with a towel, and their eyes stay clear for days.