Marek's Disease Attempted Therapies

MammaBella

In the Brooder
Dec 28, 2020
4
12
26
Hi All,

Longtime reader, but first-time poster! Sorry for the garbled explanation that comes next, but I'm looking for some guidance on Marek's Disease in 3-month-old chicks.

I've read a few posts on Backyard Chickens that address the scourge that is Marek's Disease. Although I'd heard of Marek's in passing (nowhere near as frequently as Coccidiosis) it never crossed my mind until I adopted two chicks in early Nov. I previously/currently have a flock of mostly ISA brown ex-battery girls (an ISA rooster) (Ginger, Poppy & Moose), an Australorp (Daisy), and an extreeeeemely broody Plymouth Rock (Dot). My shenanigans began in late October when Dot decided she wasn't going to leave the nest, coming into Summer we thought it might be nice for her to have two bubs of her own. When none of our eggs hatched and appeared chickless, we felt it was time to give Dot some babies of her own. I located a local breeder (which I realise now was my first mistake) and collected two beautiful little bubs from her - Dolly and Dede (Sussex x Rhode Island Red & Plymouth Rock x Rhode Island Red). All was going well until last Monday, when I found Dede paralysed in her nest box, after a trip to the vet it was confirmed as Marek's Disease. It's now Monday of the second week, Dede is still with us, and tomorrow I am going to try Acyclovir and St. John's Wort (maybe Lysine later if we get to that stage), I am also thinking of buying Avi-Vital to give her some extra nutrition.

My question is, does anyone know how to accurately measure out the dosage of Acyclovir for a small chick (she is around 3 months old - but still light in my hands) I am also planning to get Zovirax in tablet form (500 mg) and wondering how to measure out the 10 mg powder (thinking maybe a pipet?) or would it be better to use the small syringes from the vet (currently used for giving Meloxicam 0.25 mL AM/PM). Any help would be greatly appreciated!
 
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I have no experience with giving acyclovir or dosage. Isn’t Zovirex the same as acyclovir? Your vet might know a dosage. There is not presently a treatment for Mareks, although many do try certain supplements or medicines on their own. Your rescue battery hens also could have been carriers of Mareks. We never know when we bring in unvaccinated birds from different sources. Sorry that you are dealing with Mareks. I would read all you can about the disease. Here are a couple of good articles to read:
http://csu-cvmbs.colostate.edu/Documents/vdl-mareks-disease-fact-sheet.pdf

https://www.backyardchickens.com/articles/the-great-big-giant-mareks-disease-faq.66077/
 
Hi All,

Thanks for the welcome! I'm trying Vaclovir? Apparently a more potent form of Acyclovir - I ended up shaving some off a 500 mg tablet and giving via a drip, I also gave her St. John's Wort (mixed with demineralised water) so I'll keep you posted on any progress.

Happy to join the chat!
 
Quick update, Dede is still with us and her mobility has improved a little bit and her previously closed eye is partially open. I am treating her with a mix of St. John's Wort, Lysine, and Vaclovir (approximately 10 mg to 25 mg) depending on how much I can shave off the 500 mg tablet!

She's in great spirits, however, has been passing caecal worms I think - so it's off to the pet shop for more wormer. Her sister Dolly is still completely fine, but just in case I have added Lysine to the water my adult hens + Moose drink to hopefully stave off the development of tumours. So, fingers crossed!
 

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