Carolei, the goal of the vaccine is to provide exposure to Marek's in a chick and the blood will start to manufacture antibodies without the chick getting Marek's. The vaccine itself has no preventative medicine in it. It's just a safe exposure, and chicks should be quarantine for a few weeks following the vaccine.
The idea is to give a chick a jump start so that when exposed to the deadly virus, it can already have antibodies.
If you want to do this safely, you would have to take the eggs before they hatch, hatch them, quarantine them for 3 weeks, and give them back. I'm not sure if a hen will accept them back. I do know that I had a Buff Orpington adult who I put 3 Jersey Giants in with at 6 weeks old, and at night they roosted together and she spread her wings over them.
I tried twice with broody hatched eggs and was not successful. So I quit.