Unless they are hurting the small female, I would let nature alone.
Years ago I had 2 male cats, they took turns doing each other. Neither was complaining (meowing) so I just let it go. They were both neutered and both grew up to to be old men together.
Years ago I had 2 male cats, they took turns doing each other. Neither was complaining (meowing) so I just let it go. They were both neutered and both grew up to to be old men together.