Never use Nu-Stock near any mucous membranes and that includes the vent. It is a mange medicine labeled for horses and dogs that works well for scaly leg mites and that's it. Soap and water won't "clean" a coop. Disinfectants like Oxine AH, Biophene will, along with eliminating viruses, bacteria, fungi. Whitewash has mild antimicrobial properties but won't do much against external parasites. Emulsified concentrates of permethrin/Rabon-Vapona are preferred and labeled for use around and on poultry. Chemicals can be organic or synthetic. Permethrin is derived from pyrethrin, an organic chemical that comes from daisies.Nustock ointment on the vent and legs may help the situation.
If it is gleet I would do the same.... but you can use a cool natural baby wipe smothered with nustock to clean the area.
But then chemicals can irritate and cause rashes like that too. I don't use any of the type you describe. DE can cause problems too.
I'd be more inclined to treat with epsom salt soaks for legs and nustock on bottom and legs combined with a thorough coop cleaning with soap and water. Then if you haven't already a white wash applied to coop interior and all wood crevices may help deter/kill any remaining insects.
Many will disagree with me but the more natural and less chemical the better.
Do they free range..... not penned?
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