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Some chick down color can be culled at hatch once you have learned the line and variety well. We learned after the first year which columbians colored out better based on chick down coloration but that varied based on teh lines, Blues are tougher, and Blue laced varities were tougher to cull as chicks.
Based on comb defects as early as possible, color based on variety, type and feather quality 5-7 months, Some type issues and feather quality can be caught earlier but you really have to wait a while for some to finish out more, I like to wait on the best cockrells till around 10-12 months but seldom breed out of them other than fertility testing until after the first full adult molt.