In my opinion, its quite possible that they won't. New chickens thrown into a new pecking order can be treated brutally. Imagine the treatment for a much smaller, crested breed. You large rooster mating small Silkie hens could also be a recipe for disaster.
Yes, its absolutely possible to integrate some Silkies into a flock of standard sized birds, I'm not trying to discourage you there. But, it needs to be done with utmost care and a very watchful eye. Silks are an extremely docile breed (most of them anyway) which gives tendency for them to be picked on. If you end up with big crested birds like the girl in my avatar, they don't see well. They don't roost because of their shredded feathers, and alot have a soft spot on their head (like a baby). For some the soft spot closes with age, for others it does not. A peck there can cause all sorts of neurological problems.
I recommend checking out the Silkie thread, read, read, read and then determine if you think they'd be a good fit for you.
Good luck, again- I'm not trying to discourage you, but I've read tons of horrible posts about injured or mentally handicapped little Silkies because someone wanted to "throw a few in" with their big girls.
Nikki