Sometimes if raised together, females will be ok, sometimes not. If you want to keep them together, it is best to have them spayed & neutered.
If you keep a male and female together that are not fixed, the female will have a litter and may end up destroying it, or the male might, after they are born, due to being in the cage together. The male will also rebreed the female within days of the litter being born and you will have a second litter being born before the first litter is hardly weaned. Then you have all these babies and issues again with males and females and fighting, inbreeding, etc.