Beside the long list of animal enemies there's always the slight chance that an idiot human might trespass and walk past your run. Especially in urban yards. All idiot humans need is to see one of your chickens roosting outside in the run. They're capable of a lot more damage than anything smaller than a bear.
On the other hand, if the chickens are all sleeping unseen inside the coop behind a tightly shut door, the likelihood of any devilment is a lot less, and you can relax with the notion that you've done everything you can.
On the other hand, if the chickens are all sleeping unseen inside the coop behind a tightly shut door, the likelihood of any devilment is a lot less, and you can relax with the notion that you've done everything you can.