"These data reveal that Rp maps to a region of Gga 2 that is distinct from the predicted location of genes previously associated with caudal truncation [10]–[14]. The 0.74 Mb critical interval contains the Iroquois homeobox genes, Irx1 and Irx2. The Iroquois genes encode transcription factors that function in patterning and regionalization of tissues early in development [15]. Irx1and Irx2 are prepattern and proneural genes first identified in Drosophila and Xenopus [16],[17]. Studies of gene function suggest that Irx genes have redundant yet distinct roles in development [18], [19]. Irx genes have been knocked out in mice and zebrafish with little effect on tail development [19]–[23]. However, the rumpless phenotype is dominant, suggesting that misexpression of Irx1 or Irx2 may underlie the trait, rather than loss of function."
So perhaps the partial tail is due to misexpression of the Irx genes responsible for early development of the vertebrate.
So perhaps the partial tail is due to misexpression of the Irx genes responsible for early development of the vertebrate.