A few months ago, I brought home a silkie. She had a runny nose. When it cleared up, I put her in with the other silkies. A month later, my silkie roo was sleeping all day and not eating. I separated him, and started him on LS-50. In 3 days the discharge stopped, and he was 100%, but I continued the antibiotics for 7 days. I don't know. The clear runny nose doesn't really fit into anything other than the sniffles or a cold. My other 4 silkies didn't get sick. I like LS-50, and others like Tylan. They are both really good for respiratory issues.