Actually I've only taken Percocet twice in my life and it did nothing for pain either time. So I have no resistance to it which is why I thought for sure it would work, but nada. Vicodin was prescribed a little over a month ago for a back injury, and it is what is prescribed for treatment of pelvic pain that is awaiting a hysterectomy. It did nothing, or if it did anything it may help for 30 minutes max. I don't take it but maybe once or twice a week when I know I'm going to be hurting. I was referred to pain management but didn't keep the apt. I'd just rather not do that. In my case I just seem to have a tolerance for medication. And If I don't have a tolerance for it then I tend to have a bad reaction to it. I stick to ibuprofen...