I just used it yesterday on my broody and her nest, which was completely infested. I tried the method of putting her in a paper bag with her head sticking out, then sort of hitting the bag to make the powder puff up around her. I don't recomend that. She freaked out, thrashed around, and ripped the bag up with her feet. I got some on her that way, then just finished by putting some in my hand and rubbing it all over her. I shoveled out the bedding in her nest box, as well as some of the dirt, and put a layer of powder in before putting new shavings on top of that. I also made sure to sprinkle some in the corners. Her babies are due to hatch on Friday, so I really hope I've taken care of it and they will be okay with the dust in there. Othewise they would have been killed by the mites (red ones), there were SO MANY!