Duck not able to walk

Vitamin Supplementation, specifically B3(niacin) is not going to hurt, will likely help but since you said it was an overnight occurrence I highly doubt that is the sole cause of the problem. I would be more inclined to think a sprain of some sort. Just keep her in an area that's going to limit her mobility, so she doesn't further injure anything, provide soft bedding, administer some b vitamins, and do some water therapy and let us know if she improves.
 

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