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To some extent, yes, especially if it has only been in the incubator a few days. The more sudden the movement, the more likely this is to happen. With experience, you come to learn the difference between what is normal and what is abnormal. Slight movement, sort of more like quivering, is ok. If the whole thing sloshes around, that is bad. Not always fatal, I've been incubating geese this spring from shipped eggs, they mostly came with severely detached air cells, but with a little time and very gentle handling, the air cells did stabilize. They didn't have a good hatch rate at all, but most of them did at least develop, and what I found ironic was that a couple of the ones that hatched were the ones with the worst movement originally, which is the opposite of what I had expected.