eggchel...

[Rafter 7 Paint Horses]

Did you ever find out what caused your rabbit to die? I'm curious, a friend has one right now that is showing the same symptoms, and I would like to be able to tell her what is was that yours had, so maybe it will help her.

Thanks,
Jean

 

[eggchel]

Hi Rafter7, I got the report but wasnt really clear on the diagnosis. Here is the latest report. I hope your friend's bunny is okay.

chel

Preliminary Accumulative Report #2 - Printed: 02/13/07
California Animal Health & Food Safety ACCESSION#:
Laboratory System (CAHFS) - Davis District: 4
L A B O R A T O R Y F I N D I N G S / D I A G N O S I S
1. Cerebral and meningeal hemorrhage.
2. Pulmonary edema.
3. Nephrosis; bilateral, moderate, diffuse, with proteinaceous cast
formation.
4. Hepatocellular necrosis; moderate, midzonal to periacinar.
A C C E S S I O N S U M M A R Y
02/13/07:
Please note rabies test result has been negative for this case.
02/08/07:
Histological changes noted are suggestive of a septic process involving
several organs. However, bacteriology testing did not yielded any significant pat
hogen is
isolate from liver and the lung. Please note Pasteurella multocida has
been isolated from the brain. Additional tests are still pending.
02/06/07:

I am unable to determine at this stage the exact underlying pathological
process and the cause of death in this animal. I have submitted appropriate
samples for ancillary tests including FA test for rabies. The results of
these tests would assist in establishing the main disease process and
possible etiology.
G R O S S P A T H O L O G Y
The submission is the carcass of a female rabbit of unknown age, presented
dead. Postmortem condition is fair and nutritional body condition is fair.
No significant external abnormality is noted. Trachea is mildly congested
and the right lung shows extensive patchy red discolored areas throughout.
Liver is moderately enlarged and appears somewhat mottled on the surface
however the consistency appears to be normal. Stomach is mildly edematous
with the presence of excessive volume of mucus mixed with small amounts of
green ingesta. The rest of the gastrointestinal tract is unremarkable.
Spleen is unremarkable. Kidneys are unremarkable and heart is unremarkable.
No other significant gross abnormality is detected in this animal.
H I S T O P A T H O L O G Y
Examined are sections of brain, skeletal muscle, tongue, heart, lung, liver,
spleen, pancreas, uterus, kidney, trachea, esophagus, stomach, small and
large intestine. Scant hemorrhages are found in various locations in the
brain. Meninges are generally congested with multifocal hemorrhages.
Multifocal to coalescing areas of lung contain eosinophilic material filling
the alveolar space. Numerous vessels are noted that contain fibrin clot.
Areas of lung show severe diffuse congestion. There is mild to moderate
hepatocellular degeneration and necrosis predominantly in
periacinar to midzonal areas. Kidneys show diffuse moderate degenerative
changes affecting the renal tubules. Numerous tubules are noted with
proteinaceous casts. Multifocal interstitial hemorrhage is noted throughout
the kidney. Small foci of pleocellular inflammatory aggregates are also
noted in the interstitium. Proteinaceous casts are noted both in the cortex
and the medulla. Several capillaries are noted in the submucosa of trachea
which contains fibrin clots. Segments of small intestine contain a moderate
diffuse eosinophilic infiltrate in the lamina propria. Histiocytic
infiltrates are also noted in the center of Peyer's patches that contain
light brown pigment.
V I R O L O G Y
*** RABIES (YOLO COUNTY HEALTH)
BRAIN negative
T O X I C O L O G Y
The detected liver mineral concentrations are within acceptable ranges for
rabbits.
MDL = method detection limit (lowest concentration detectable by our
test method).
VITAMIN E
LIVER Pending
*** HEAVY METAL SCREEN
Specimen Type LIVER
Metal Arsenic Cadmium Copper Iron Lead
MDL 1 PPM 0.3 PPM 0.1 PPM 0.2 PPM 1 PPM
< 1 PPM < 0.3 PPM 6.4 PPM 264 PPM < 1 PPM
Metal Manganese Mercury Molybdenum Zinc
MDL 0.04 PPM 1 PPM 0.4 PPM 0.1 PPM
2.41 PPM < 1 PPM < 0.4 PPM 62.7 PPM
*** SELENIUM - TISSUE/OTHER
LIVER 0.635 ppm Wet Weight 0.020 ppm
P A R A S I T O L O G Y
FECAL EXAM - DIRECT WET SMEAR
FECES No parasites seen
B A C T E R I O L O G Y
BACTERIAL AEROBIC CULTURE
LIVER No growth - In 48 Hrs.
LUNG No growth - In 48 Hrs.
BRAIN Mixed flora Rare
Escherichia coli Rare
Pasteurella multocida Rare
SALMONELLA CULTURE - MAMMALIAN
FECES No Salmonella sp. detected
LISTERIA CULTURE - COLD ENRICHMENT
BRAIN ending​

 

[Rafter 7 Paint Horses]

Thanks, but hers didn't make it either.

I sure wish they would put reports in plain English so we can understand it completely.

Thanks for posting the report, maybe someone with a medical background will read it and clarify it for us.


Jean

 

[soonerdog]

1. Cerebral-(brain) and meningeal-(membranes covering the spinal cord and brain) hemorrhage-(blood loss;possibly refering to bleeding in the cranium (skull), bleeding in the brain).
2. Pulmonary-(pertaining to the lung) edema-(pertaining to swelling).....swelling of the lungs.
3. Nephrosis-(abnormal condition of the kidneys); bilateral-(both kidneys), moderate, diffuse, with proteinaceous cast
formation.
4. Hepatocellular-(pertaining to the liver cell activity) necrosis-(the death of cells, tissue, and organs) ; moderate, midzonal to periacinar.
A C C E S S I O N S U M M A R Y
02/13/07:
Please note rabies test result has been negative-(not found, none) for this case.
02/08/07:
Histological-(pertaining to tissue studies) changes noted are suggestive of a septic-(poison or toxins) process involving
several organs. However, bacteriology-(study of bacteria) testing did not yielded any significant pat
hogen-(bacteria causing disease) is
isolate from liver and the lung. Please note Pasteurella multocida has
been isolated from the brain. Additional tests are still pending.
02/06/07:

I am unable to determine at this stage the exact underlying pathological-(study of disease)
process and the cause of death in this animal. I have submitted appropriate
samples for ancillary tests-(second sets of test; additional tests) including FA test for rabies. The results of
these tests would assist in establishing the main disease process and
possible etiology-(study of unknown causes for the disease.....some diseases have no known causes).

Hi Chel,
I attempted to plug in some medical terminology that might help you to understand what went wrong with your bunny. I can not diagnose its condition, even they are puzzled as to really what caused all of these issues with the bunny having multiple organ failures. I know you must be concerned about the rest of your bunnies catching what ever this may be. Hopefully it is nothing that will spread to the others. I can see where they did tissue studys from the lung, and liver, and feces tests and have determined that there are no pathogens-(disease causing bacteria). So that is good to know that there is probably not a bacteria that the others could have contacted from this bunny. Again, I can not diagnose and should refrain from attempting it. I am just a student studying medical terminology and thought I would share some insight. I am so sorry to hear about your loss. Johnny