ButtonquailGirl14
Crossing the Road

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Fowl cholera can cause swelling of the face, wattles, or comb, but you would probably be seeing a much sicker bird. That is why trying the benadryl for some sort of bite or sting might be helpful. I will check back in tomorrow morning.
How deep does that hole go?
Does it look "fresh" like it was done today or is it possible she was injured earlier in the week and the scab was just now picked/pulled off?
I really don't know quite what to make of all the swelling, I would try the Benadryl as suggested to see if that makes a difference.
It might help if we could get a better look at the hole. Is it possible she had some sort of abscess that ruptured through the skin? Did the hole appear after the swelling started?
I do wonder like @micstrachan if it was an abscess or cyst that burst. Can you take a closer look at the wound and tell if it looks like a puncture wound or possibly something that ruptured.
How did you treat the wound - flush it or anything like that? Wetted feathers make it easier to see. You can use saline, soap/water, whatever you have on hand.
Vetericyn is the good stuff!I used a swab sprayed with Vetericyn plus (the gel style) and rolled it against the hole to clean it 3x. Then I sprayed it directly into the hole.
We can try to flush it in the morning by bringing her in the bathroom and squirting some betadine/water solution into it.
Signing off for the night. Have to go to work in the morning and try to manage this over the phone and on my lunch break.