Hello! I am really struggling with UTIs in my 5.5 month old F Mastiff. I am hopeful someone on here can offer some insight or possibilities of why this is happening.
History thus far:
Picked up puppy at 8 weeks
We are struggling with potty training so decide to check urine at 12 weeks. Comes back clear.
5 days later she has a raging UTI, blood, mucas and squatting/dribbling every few minutes. Don't ask, I was in ER 2 days after tested clear and in bed resting only to get up and discover what hubs was missing

Take her to ER, get 10 day course antibiotics and pain meds
Test urine on day 10 comes back clear but I do not believe it is gone so send a clean catch 48 hrs later to be cultured.
Culture was positive, showed amoxicillin sensitivity so started a 3 week course of treatment.
36 hrs after last amox dose symptoms are back. Do another clean catch culture.
I noticed her recessed vulva at this time and start cleaning her throughout the day.
Start sulfa (against Dr liking but culture would take a couple days) and I saw the best improvement as of yet.
Culture came back positive. It was still sensitive to amox so dr decided on another 3 week treatment of amox because strong Sulfas are not a good option for puppies.
2 weeks into treatment still has UTI symptoms and they are getting worse so decide to take off amox and get a clean catch urine culture, again. Start another sulfa, not quite as strong as first one.
Run blood work which is all normal. Dr conformed a pretty bad recessed vulva but said I am cleaning well.
Culture comes back positive with a sensitivity to nearly all antibiotics, including the 4 we have already tried.
Current plan is to finish the sulfa, start a maintenance dose of amox after, continue pain med for comfort while we wait for our appointment with internal medicine at the U of I.
Ok, what gives??? I am beyond boggled as to why! Can this be congenital or inherited? I am doing everything possible to treat it properly. She is very rarely locked up for any amount of time with 7 hrs only happening 2X since getting her. I don't believe we are the cause of this.
She is from a breeder and has a health guarantee but seriously, how do you trade your puppy in for a new one because of chronic health issues?
Anyways, if you've made it this far thank you, I really appreciate it. If you have experienced, or know someone or have even heard of anything like this please share. I am really at a loss and getting frustrated
Thank you.
History thus far:
Picked up puppy at 8 weeks
We are struggling with potty training so decide to check urine at 12 weeks. Comes back clear.
5 days later she has a raging UTI, blood, mucas and squatting/dribbling every few minutes. Don't ask, I was in ER 2 days after tested clear and in bed resting only to get up and discover what hubs was missing


Take her to ER, get 10 day course antibiotics and pain meds
Test urine on day 10 comes back clear but I do not believe it is gone so send a clean catch 48 hrs later to be cultured.
Culture was positive, showed amoxicillin sensitivity so started a 3 week course of treatment.
36 hrs after last amox dose symptoms are back. Do another clean catch culture.
I noticed her recessed vulva at this time and start cleaning her throughout the day.
Start sulfa (against Dr liking but culture would take a couple days) and I saw the best improvement as of yet.
Culture came back positive. It was still sensitive to amox so dr decided on another 3 week treatment of amox because strong Sulfas are not a good option for puppies.
2 weeks into treatment still has UTI symptoms and they are getting worse so decide to take off amox and get a clean catch urine culture, again. Start another sulfa, not quite as strong as first one.
Run blood work which is all normal. Dr conformed a pretty bad recessed vulva but said I am cleaning well.
Culture comes back positive with a sensitivity to nearly all antibiotics, including the 4 we have already tried.
Current plan is to finish the sulfa, start a maintenance dose of amox after, continue pain med for comfort while we wait for our appointment with internal medicine at the U of I.
Ok, what gives??? I am beyond boggled as to why! Can this be congenital or inherited? I am doing everything possible to treat it properly. She is very rarely locked up for any amount of time with 7 hrs only happening 2X since getting her. I don't believe we are the cause of this.
She is from a breeder and has a health guarantee but seriously, how do you trade your puppy in for a new one because of chronic health issues?
Anyways, if you've made it this far thank you, I really appreciate it. If you have experienced, or know someone or have even heard of anything like this please share. I am really at a loss and getting frustrated

Thank you.