I think the coop will be your limiting factor, in winter you will see enough snow and bad weather they will be stuck in the coop a lot. That run area will go days without being used. It will be interesting to see what
@aart has to say but I'd probably limit it to ten hens of those breeds or chickens that size. And do any integration in the good weather when all that run space is available.
Personally I'd build a separate coop for the ducks. The reason for that is that you want the chicken coop to be dry and ducks need a lot of water and can make a mess.