I suffer from multiple migraines in any given week. They are quite debilitating and I have had almost no success in control over them. At one point I was on Depo-Provera (to stop hormone related attacks)and I had almost no migraines at all but even that eventually got to the point where it was not working anywhere near as good as when I first started on it. Edited to add. I take Relpax now but it does not always work and makes me very sick sometimes.