I work with a lady who suffers from them. I wasnt sure about how bad they were till I met her. She works her tail off and has no qualms about working if shes sick, etc. Her tolerance for pain is very high. However when she has a migraine, shes on the floor. So that lets me know how bad they are. I believe her doctor found a pill that lets her cope. She takes one at the very first sign of a migraine and it usually helps considerably. I know she used to have to go to the ER and get shots of something to make them go away.