After my first child, my DH picked up MRSA from the hospital. He had it about 10 months before I finally picked it up from him. We have the "community-associated" MRSA, so it has (so far thank goodness) only been on the skin.
It was 2 years before a newbie nurse at the doctor's office recognized it as MRSA, and finally perscribed the correct antibiotics. According to the Mayo Clinic, MRSA is resistant to 9 of the 12 antibiotic families, so you have to be taking the correct antibiotic for it to work.
MRSA is also carried by most people in their noses---so keep your fingers outta there! If you have MRSA in your family, get the doc to give you the topical goop (miripricin?). You'll have to swab the nasal cavities of EVERYONE in the house for 30 days.
Soap and Water (not antibiotic soap) all the time.
The swelling can get pretty bad, especially if the infection is on a fatty area. Wait until the purulence feels fluctant before trying to drain. This could be day 4 or 5 of infection. Best to let a doctor do it, but if you are going to give it a go---wear gloves and sanitize everything before and after.