If the pain is severe and you are an adult -CHECK WITH A PHARMACIST FIRST-you can take 4 advil and after 4 hours take 3 tylenol, then keep alternating. Check with an actual pharmacist but often dental pain won't respond to a couple of advil and then it is ok to exceed the recommended dosage. Try starting with 2 advil (ibuprofen) and if you need more, take 2 more.