I have not heard anything negative about Tylan 50. I was hoping for an alternative that I could give her immediately. Our local feed store is a mom and pop store that will have to order the medicine. I gave her some water with boosted with probiotics and electrolytes ( Brand: Sav A Chick) and kept her warm in the house and I think the wheezing is calming down
Tylan 50 and 200 can be good antibiotics to treat mycoplasma (MG) and coryza. If you are just dealing with a virus, such as infectious bronchitis, then you may not need Tylan. Tylan injectable is about the only antibiotic available in feed stores any more since the beginning of 2017. For use, a 3ml syringe with a 22 gauge needle can be used to with draw the medicine from the vial. It can be given into the breast muscle , but some prefer to give it orally (take the needle off the syringe.Here is some infor about the difference between IB and MG:
Infectious Bronchitis
Synonyms: IB, bronchitis, cold
Species affected: Infectious bronchitis is a disease of chickens only. A similar disease occurs in bobwhite quail (quail bronchitis), but it is caused by a different virus.
Clinical signs: The severity of infectious bronchitis infection is influenced by the age and immune status of the flock, by environmental conditions, and by the presence of other diseases. Feed and water consumption declines. Affected chickens will be chirping, with a watery discharge from the eyes and nostrils, and labored breathing with some gasping in young chickens. Breathing noises are more noticeable at night while the birds rest. Egg production drops dramatically. Production will recover in 5 or 6 weeks, but at a lower rate. The infectious bronchitis virus infects many tissues of the body, including the reproductive tract (see Table 1). Eggshells become rough and the egg white becomes watery. (See publication PS-24, Egg Quality, for other causes of poor egg quality.)
Transmission: Infectious bronchitis is a very contagious poultry disease. It is spread by air, feed bags, infected dead birds, infected houses, and rodents. The virus can be egg-transmitted, however, affected embryos usually will not hatch.
Treatment: There is no specific treatment for infectious bronchitis. Antibiotics for 3–5 days may aid in combating secondary bacterial infections. Raise the room temperature 5°F for brooding-age chickens until symptoms subside. Baby chicks can be encouraged to eat by using a warm, moist mash.
Mycoplasma gallisepticum
Synonyms: MG, chronic respiratory disease (CRD), infectious sinusitis, mycoplasmosis
Species affected: chickens, turkeys, pigeons, ducks, peafowl, and passerine birds.
Clinical signs: Clinical symptoms vary slightly between species. Infected adult chickens may show no outward signs if infection is uncomplicated. However, sticky, serous exudate from nostrils, foamy exudate in eyes, and swollen sinuses can occur, especially in broilers. The air sacs may become infected. Infected birds can develop respiratory rales and sneeze. Affected birds are often stunted and unthrifty (see Table 1).
There are two forms of this disease in the turkey. With the "upper form" the birds have watery eyes and nostrils, the infraorbitals (just below the eye) become swollen, and the exudate becomes caseous and firm. The birds have respiratory rales and show unthriftiness.
With the "lower form", infected turkeys develop airsacculitis. As with chickens, birds can show no outward signs if the infection is uncomplicated. Thus, the condition may go unnoticed until the birds are slaughtered and the typical legions are seen. Birds with airsacculitis are condemned.
MG in chicken embryos can cause dwarfing, airsacculitis, and death.
Transmission: MG can be spread to offspring through the egg. Most commercial breeding flocks, however, are MG-free. Introduction of infected replacement birds can introduce the disease to MG-negative flocks. MG can also be spread by using MG-contaminated equipment.
Treatment: Outbreaks of MG can be controlled with the use of antibiotics. Erythromycin, tylosin, spectinomycin, and lincomycin all exhibit anti-mycoplasma activity and have given good results. Administration of most of these antibiotics can be by feed, water or injection. These are effective in reducing clinical disease. However, birds remain carriers for life.