Everything I can find is about using it in cows/sheep/goats and it's injected into the lower eyelid. Also said on one site to flush with water if it contacted the eye as it could cause irritation. I would be reluctant to use it in the eye, and I would think it would be difficult to inject into a chickens eye lid. I personally would stick with something that is intended by design to be used in the eye, unless i was working directly with a vet.