How did I do OZ? Not too kooky of advice?
I better respond in 2 parts
Part 1
The best treatment for fatigue is sleep. 8 hours of uninterupted sleep. If your not rested in the morning or are dozing by 1pm, eaxamine sleep patterns.
Exercise, diet and hydration will improve your overall energy.
Part 2
Why does vitamin B12, among all the vitamins, have a halo of benefit for fatigue and energy levels?
The answer is part science and a whole lot of marketing
.
Here are some fun facts:
Vit B12 is absorbed in the last part of the jejunum – a long, long way down the GI tract. Sub-lingual or under the tongue B12 is no more readily absorbed. (Aplogies to the quack, Dr. Mercola, and snake oil peddling Dr Oz).
Vit B12 is one of the few vitamins that are stored well by the body. It takes 3-5 years to deplete the Vit B12 levels in the body. Deficiency is never the result of any short-term issue. The usual (non-vegetarian)
“Western” diet provides 5-7 mcg of B12 per day, which is more than adequate to maintain appropriate levels: the RDA is 2mcg/day and 2.6mcg/day in pregnancy.
When it comes to demonstrated efficacy, B12 has only been conclusively established to be effective for preventing or treating B12 deficiency.
Causes of B12 deficiency
Pernicious anemia is a consequence of an immune reaction that destroys the stomach’s ability to secrete intrinsic factor, which is essential for most of our B12 absoption. No intrinsic factor = little B12 absorption = pernicious anemia. Pernicious anemia develops slowly, over decades – it’s most common in the elderly, and rare in those under 30.
Vegetarians and vegans that do not consume animal products must take a supplementary source of B12
Outside of these groups, dietary deficiency is rare.
Other medical conditions can cause deficiency through a reduction in absorption, all of which may be more prevalent in older adults:
- gastritis and H. pylori infection
- intestinal effects and consequences of from gastrointestinal disease, cancer, or HIV
- reduced gastric acid secretion secondary to drug therapy like proton pump inhibitors
- other drugs, like the diabetes drug metformin, which can have gastrointestinal effects
The Framingham study with a cohort of non-institutionalized adults 67 through 96 years of age found that 5.3% of the participants had serum vitamin B12 levels that were mildly deficient of which 80% had no symptoms.
If you have mild deficiency, a tablet containing 1000mcg (of which 1% will be absorbed) daily will reduce and then reverse symptoms.
edited to add references
References
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884303/?tool=pmcentrez
http://www.medscape.com/viewarticle/585589?src=mp&spon=30
http://www.cdc.gov/ncbddd/b12/references.html