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Updated - Corid and Amprol (amprolium) Dosing

Discussion in 'Peafowl' started by casportpony, Aug 26, 2013.

  1. casportpony

    casportpony Poop Inspector General Premium Member

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    Due to some confusion on dose amounts regarding the powder, I decided to do some research and this is what I have so far. For those of you that use powder Corid, if you have been using 1/2 teaspoon per gallon (~270mg) you haven't been using enough.

    The preventative dose (.006%) for Corid Powder is 1/3 teaspoon.
    The preventative dose (.006%) for Corid liquid is 1/2 teaspoon.


    The moderate outbreak dose (.012%) for Corid Powder is 3/4 teaspoon.
    The moderate outbreak dose (.012%) for Corid liquid is 1 teaspoon.


    The severe outbreak dose (.024%) for Corid Powder is 1.5 teaspoons
    The severe outbreak dose (.024%) for Corid liquid is 2 teaspoon.


    Corid mixing instructions for preventative (.006%) and moderate (.012%) outbreak dosing.
    http://www.corid.com/SiteCollectionDocuments/CORID Slim Jim-All.pdf


    Amprol 20% powder:
    http://www.asp-inc.com/products/documents/prodinfo/a/amp128.pdf


    Amprol 9.6% liquid:
    http://www.asp-inc.com/products/documents/prodinfo/a/amp96.pdf


    FDA recommendations:
    http://www.accessdata.fda.gov/scripts/animaldrugsatfda/details.cfm?dn=013-149
    "Chickens
    Indications: For the treatment of coccidiosis.
    Amount: Administer at the 0.012 percent level in drinking water as soon as coccidiosis is diagnosed and continue for 3 to 5 days (in severe outbreaks, give amprolium at the 0.024 percent level); continue with 0.006 percent amprolium-medicated water for an additional 1 to 2 weeks."


    And this link has these instructions:
    http://www.drugs.com/vet/amprol-9-6-solution-can.html
    "Poultry - as Soon As Caecal Coccidiosis Is Diagnosed, Give 0.024% Amprolium In The Drinking Water For 5 To 7 Days. Continue The Treatment With 0.006% Amprolium Medicated Water For An Additional One To Two Weeks. No Other Source Of Drinking Water Should Be Available To The Birds During This Time."


    Here's the math, let me know if I made an error.

    • There are 200mg of amprolium in every 1 gram of powder.
    • 1 ounce = 3.5 tablespoons = 28.35 grams
    • 200mg x 28.35 = 5670mg in 3.5 tablespoons of powder.
    • There are 10.5 teaspoons in 3.5 tablespoons
    • There are 21 1/2 teaspoons in 10.5 teaspoons
    • 5670mg divided by 21 1/2 teaspoons = ~270mg per 1/2 teaspoon
    • There are two 1/4 teaspoons per 1/2 teaspoon
    • 270 mg divided by 2 = 135mg per 1/4 teaspoon


    Amount of Amprolium (Corid or Amprol) powder per 1/4 teaspoon
    • One 1/4 teaspoon = 135 mg
    • 1/2 teaspoon = 270 mg
    • 3/4 teaspoon =405 mg
    • 1 teaspoon = 540 mg
    • 1 & 1/4 teaspoons = 675 mg
    • 1 & 1/2 teaspoons = 810 mg
    • 1 & 3/4 teaspoons = 945 mg
    • 2 teaspoons= 1080 mg


    Amount of Amprolium (Corid or Amprol) liquid per 1/4 teaspoon
    • One 1/4 teaspoon = 120 mg
    • 1/2 teaspoon = 240 mg
    • 3/4 teaspoons = 360 mg
    • 1 teaspoon = 480 mg
    • 1 & 1/4 teaspoons = 600 mg
    • 1 & 1/2 teaspoons = 720 mg
    • 1 & 3/4 teaspoons = 840
    • 2 teaspoons = 960 mg

    There are 4.92892ml/teaspoon, but the numbers above were calculated using 5ml/teaspoon
    Here is what's in 1-10ml of the liquid
    • 1ml = 96mg
    • 2ml = 192mg
    • 3ml = 288mg
    • 4ml = 384mg
    • 5ml = 480mg
    • 6ml = 576mg
    • 7ml = 672mg
    • 8ml = 768mg
    • 9ml = 864mg
    • 10ml = 960mg

    Bottom line, 1 teaspoon (540mg) of powder is equal to 5.625ml of liquid and 1/2 teaspoon powder (270mg) is equal to 2.8125ml liquid.

    1/2 teaspoon of 20% powder = 2.8125ml of 9.6% liquid - Both have 270mg of amprolium.
    3/4 teaspoon of 20% powder = 4.21875ml of 9.6% liquid - Both have 405mg of amprolium.
    1 teaspoon of 20% powder = 5.625ml of 9.6% liquid - Both have 540mg of amprolium.
    1.5 teaspoons of 20% powder =8.4375ml of 9.6% liquid - Both have 810mg of amprolium.
    1.75 teaspoons of 20% powder = 9.84375ml of 9.6% liquid - Both have 945mg of amprolium.
    2 teaspoons of 20% powder = 11.25ml of 9.6% liquid - Both have 1080mg of amprolium.




    And if that doesn't convince people, here is another way I did it:

    From:
    http://www.asp-inc.com/products/documents/prodinfo/a/amp128.pdf:


    Dosage Level Mixing Directions
    0.024% Dissolve 8 ounces of AMPROL 128 20% Soluble Powder in about five gallons of water in a 50-gallon medication barrel. Stir, then add water to the 50 gallon mark. Stir thoroughly.
    0.012% Follow same directions as above but use 4 ounces of AMPROL 128 20% Soluble Powder.
    0.006% Follow same directions as above but use 2 ounces of AMPROL 128 20% Soluble Powder.


    Facts
    • One pack = 10 oz. (283.5 grams)
    • One ounce = 28.35 grams
    • One ounce of powder = ~3.5 tablespoons
    • 200mg amprolium per 1 gram

    My twisted math for the .024% level
    If 8 ounces (28.35g x 8 = 226.8 grams) are needed for 50 gallons, then 1/50 of that is needed for 1 gallon, right? So that would be 226.8 grams divided by 50 = 4.536 grams per gallon. (doing this as I type, so correct me if I'm wrong, please!)


    So how much does a teaspoon of Corid or Amprol powder weigh? Anyone know? Well, time to break out my gram scale and do some weighing... also have a call into the mfg of Corid and I'm expecting a call back from them.

    Just got a call back from them and it is 4.536 grams per gallon. He also said that it's a very safe product and the risk of overdosing is very slim.

    -Kathy


    Disclaimer:
    In the past I have treated my chicken chicks with 2 teaspoons of the liquid for 5-7 days, that's it, but I *might* try the .006% follow up the next time I have to treat chicks.

     
    Last edited: Oct 2, 2013
  2. casportpony

    casportpony Poop Inspector General Premium Member

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    Corid info for .012% level. Double the amounts for .024%.
    [​IMG]

    [​IMG]
     
    Last edited: Sep 9, 2013
    2 people like this.
  3. cfs

    cfs Out Of The Brooder

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    Hi Kathy,

    Here's a question, what do I do if I have four chickens in the coop now? Do I follow the same dosage for a gallon and keep replacing it and hope they all drink enough? My chickens in the coop are asymptomatic, but my vet said to treat them all since one chicken was tested for coccidosis. These guys are all about 10-11 months old.
     
  4. casportpony

    casportpony Poop Inspector General Premium Member

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    If they are acting normal and not losing weight will probably drink enough, so I would treat all of them and keep a close eye on them. One way I get more medication to them is by mixing some of their crumbles with the medicated water.

    -Kathy
     
    1 person likes this.
  5. cfs

    cfs Out Of The Brooder

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    Thank you. They all seem fine now, but poor Sweety is still having issues and inside and I am concerned!
     
  6. WestKnollAmy

    WestKnollAmy The Crazy Chicken Lady Premium Member

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    I use Sulmet with Sulfadimethoxine as a back up if I can't get Sulmet. I always have it on hand for chicks so just use it for the peas.
     
  7. casportpony

    casportpony Poop Inspector General Premium Member

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    Sulmet is what I use if their coccidiosis doesn't respond to Corid. Always a good one to have!

    -Kathy
     
    Last edited: Oct 29, 2013
  8. cfs

    cfs Out Of The Brooder

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    Thank you! I think the issues were from the head trauma. I learned I need to continue the Wry Neck treatment for 3 -6 weeks and add fish oil and vitamin B complex (instead of polyvisol). I am doing that. Since adding fish oil, Sweety's feet are getting a little more stronger every day :) I am just trying to figure out how much B complex to give her since it is a tablet and she is only 3 pounds.
     
  9. Jedi Clampett

    Jedi Clampett Out Of The Brooder

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    Kathy,
    Is it ok to eat the eggs while using Corid or Amprol, or should they be discarded (similar to worming)?
    Thank you.
     
  10. WestKnollAmy

    WestKnollAmy The Crazy Chicken Lady Premium Member

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    I do not eat the eggs when using this since it can be ingested by you and affect the eggs you will be eating. I wait at least 4 days afterwards to be safe.
     
    1 person likes this.

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