Treating Coccidiosis with Corid, Amprol, AmproMed - The Correct Amprolium Dose When treating coccidisosis in my own birds I use the severe outbreak dose (0.024%) for 5 days, then the 0.006% amount for 7-14 days. Liquid dose: 2 teaspoons per gallon for five days, then 1/2 teaspoon for 7-14 days. Powder dose: 1.5 teaspoons per gallon for five days, then 1/3 teaspoon for 7-14 days. Math and references below: The FDA, FARAD, and the mfg's say this: Source: http://www.farad.org/vetgram/ProductInfo.asp?byNada=033-165 Give amprolium at the 0.012% level as soon as coccidiosis is diagnosed and continue for three to five days. (In severe outbreaks, give amprolium at the 0.024% level.) Continue with 0.006% amprolium medicated water for an additional 1 to 2 weeks. No other source of drinking water should be available to the birds during this time. Make fresh daily. So what does that mean? 20% Powder 0.024% = no less than 1.5 teaspoons per gallon 0.012% = no less than 3/4 teaspoons per gallon 0.006% = no less than 1/3 teaspoon per gallon 9.6% Liquid 0.024% = no less than 2 teaspoons per gallon 0.012% = no less than 1 teaspoons per gallon 0.006% = no less than 1/2 teaspoon per gallon Due to some confusion on dose amounts regarding the powder, I decided to do some research and this is what I have so far. For those of you that use powder Corid, if you have been using 1/2 teaspoon per gallon (~270mg) you haven't been using enough. The preventative dose (.006%) for Corid Powder is 1/3 teaspoon. The preventative dose (.006%) for Corid liquid is 1/2 teaspoon. The moderate outbreak dose (.012%) for Corid Powder is 3/4 teaspoon. The moderate outbreak dose (.012%) for Corid liquid is 1 teaspoon. The severe outbreak dose (.024%) for Corid Powder is 1.5 teaspoons The severe outbreak dose (.024%) for Corid liquid is 2 teaspoon. Corid mixing instructions for preventative (.006%) and moderate (.012%) outbreak dosing. http://www.corid.com/SiteCollectionDocuments/CORID Slim Jim-All.pdf Amprol 20% powder: http://www.asp-inc.com/products/documents/prodinfo/a/amp128.pdf Amprol 9.6% liquid: http://www.asp-inc.com/products/documents/prodinfo/a/amp96.pdf FDA recommendations: http://www.accessdata.fda.gov/scripts/animaldrugsatfda/details.cfm?dn=013-149 "Chickens Indications: For the treatment of coccidiosis. Amount: Administer at the 0.012 percent level in drinking water as soon as coccidiosis is diagnosed and continue for 3 to 5 days (in severe outbreaks, give amprolium at the 0.024 percent level); continue with 0.006 percent amprolium-medicated water for an additional 1 to 2 weeks." And this link has these instructions: http://www.drugs.com/vet/amprol-9-6-solution-can.html "Poultry - as Soon As Caecal Coccidiosis Is Diagnosed, Give 0.024% Amprolium In The Drinking Water For 5 To 7 Days. Continue The Treatment With 0.006% Amprolium Medicated Water For An Additional One To Two Weeks. No Other Source Of Drinking Water Should Be Available To The Birds During This Time." Here's the math, let me know if I made an error. There are 200mg of amprolium in every 1 gram of powder. 1 ounce = 3.5 tablespoons = 28.35 grams 200mg x 28.35 = 5670mg in 3.5 tablespoons of powder. There are 10.5 teaspoons in 3.5 tablespoons There are 21 1/2 teaspoons in 10.5 teaspoons 5670mg divided by 21 1/2 teaspoons = ~270mg per 1/2 teaspoon There are two 1/4 teaspoons per 1/2 teaspoon 270 mg divided by 2 = 135mg per 1/4 teaspoon Amount of Amprolium (Corid or Amprol) powder per 1/4 teaspoon One 1/4 teaspoon = 135 mg 1/2 teaspoon = 270 mg 3/4 teaspoon =405 mg 1 teaspoon = 540 mg 1 & 1/4 teaspoons = 675 mg 1 & 1/2 teaspoons = 810 mg 1 & 3/4 teaspoons = 945 mg 2 teaspoons= 1080 mg Amount of Amprolium (Corid or Amprol) liquid per 1/4 teaspoon One 1/4 teaspoon = 120 mg 1/2 teaspoon = 240 mg 3/4 teaspoons = 360 mg 1 teaspoon = 480 mg 1 & 1/4 teaspoons = 600 mg 1 & 1/2 teaspoons = 720 mg 1 & 3/4 teaspoons = 840 2 teaspoons = 960 mg There are 4.92892ml/teaspoon, but the numbers above were calculated using 5ml/teaspoon Here is what's in 1-10ml of the liquid 1ml = 96mg 2ml = 192mg 3ml = 288mg 4ml = 384mg 5ml = 480mg 6ml = 576mg 7ml = 672mg 8ml = 768mg 9ml = 864mg 10ml = 960mg Bottom line, 1 teaspoon (540mg) of powder is equal to 5.625ml of liquid and 1/2 teaspoon powder (270mg) is equal to 2.8125ml liquid. 1/2 teaspoon of 20% powder = 2.8125ml of 9.6% liquid - Both have 270mg of amprolium. 3/4 teaspoon of 20% powder = 4.21875ml of 9.6% liquid - Both have 405mg of amprolium. 1 teaspoon of 20% powder = 5.625ml of 9.6% liquid - Both have 540mg of amprolium. 1.5 teaspoons of 20% powder =8.4375ml of 9.6% liquid - Both have 810mg of amprolium. 1.75 teaspoons of 20% powder = 9.84375ml of 9.6% liquid - Both have 945mg of amprolium. 2 teaspoons of 20% powder = 11.25ml of 9.6% liquid - Both have 1080mg of amprolium. And if that doesn't convince people, here is another way I did it: From: http://www.asp-inc.com/products/documents/prodinfo/a/amp128.pdf: Dosage Level Mixing Directions 0.024% Dissolve 8 ounces of AMPROL 128 20% Soluble Powder in about five gallons of water in a 50-gallon medication barrel. Stir, then add water to the 50 gallon mark. Stir thoroughly. 0.012% Follow same directions as above but use 4 ounces of AMPROL 128 20% Soluble Powder. 0.006% Follow same directions as above but use 2 ounces of AMPROL 128 20% Soluble Powder. Facts One pack = 10 oz. (283.5 grams) One ounce = 28.35 grams One ounce of powder = ~3.5 tablespoons 200mg amprolium per 1 gram My twisted math for the .024% level If 8 ounces (28.35g x 8 = 226.8 grams) are needed for 50 gallons, then 1/50 of that is needed for 1 gallon, right? So that would be 226.8 grams divided by 50 = 4.536 grams per gallon. (doing this as I type, so correct me if I'm wrong, please!) So how much does a teaspoon of Corid or Amprol powder weigh? Anyone know? Well, time to break out my gram scale and do some weighing... also have a call into the mfg of Corid and I'm expecting a call back from them. Just got a call back from them and it is 4.536 grams per gallon. He also said that it's a very safe product and the risk of overdosing is very slim. -Kathy Disclaimer: In the past I have treated my chicken chicks with 2 teaspoons of the liquid for 5-7 days, that's it, but I *might* try the .006% follow up the next time I have to treat chicks.