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Tiamulin 12.5%, dosed per [COLOR=005CB1]Novartis: The dosage for chickens and turkeys is 25 mg tiamulin/kg bodyweight or 100mls of Denagard 12.5% Oral Solution for 500 kgs of bird. Denagard should be administered continuously in the drinking water at a level of 0.025% (250ppm) for 3-5 days to chickens and 5 days to turkeys.[/COLOR]

Call me math impaired...

Can you show me how the amounts you provided map out? Clearly I am missing something. I got this right off of Novartis' web site, linked above.
Ask Kathy, she mapped it out... @casportpony please help here?
 
I actually gave my best buddy an ovation for a tapeworm picture.
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Well...this can't be right. I haven't posted any pics of worms.
 
More on Denagard - and sorry if this makes it more confusing:
Denagard - treatment dose is 2 ml per liter, or 7.57ml per gallon.

Quote: Denagard 12.5% w/v Concentrate for Oral Solution
Dosage and administration
Pigs: The dosage is 8.8 mg of the active substance per kg bodyweight daily, (equivalent to 10 ml Denagard 12.5% Concentrate for Oral Solution per 142 kg bodyweight) administered in the drinking water of pigs for 3 to 5 days, depending on the severity of the infection and/or the duration of the disease.
The contents of each 1 litre bottle will treat 188 pigs of 25 kg bodyweight for three days or 114 pigs of 25 kg bodyweight for 5 days.
To ensure an intake of 8.8 mg/kg daily, Denagard 12.5% Concentrate for Oral Solution may be administered in one of two ways.
1.​
Administer in approximately one half of the daily water requirements, to ensure consumption of the correct dose. Unmedicated water should be provided each day after the medicated water has been consumed. The dosage rate, calculated on a liveweight basis, is equivalent to 10 ml solution per 142 kg bodyweight
2.​
Administer continuously at a level of 60 ppm of active substance in the drinking water, as the only source of drinking water. The daily requirement should be added to the drinking water at the rate of 9.6 ml solution per 20 litres (4.5 gallons) of water.
Where a water medicator is used the appropriate stock solution should be made up according to the maker's instructions. If there is no response to treatment within 5 days, the diagnosis should be re-established.

Chickens: The dosage for chickens is 25 mg of active substance per kg bodyweight (equivalent to 100 ml of product per 500 kg bodyweight). Tiamulin should be administered continuously at a level of 0.025% (250 ppm) in drinking water (2 ml product per litre of water) for 3 – 5 days and will provide approximately the following daily dosage of tiamulin depending on the age of the bird:
Day old chick: 125 – 150 mg/kg bodyweight
4 week old broiler: 30 – 50 mg/kg bodyweight
10 week old pullet: 30 – 45 mg/kg bodyweight
Layer: 25 mg/kg bodyweight
Turkeys: The dosage for turkeys is 25 mg of active substance per kg bodyweight (equivalent to 100 ml of product per 500 kg bodyweight). Tiamulin should be administered continuously at a level of 0.025% (250 ppm) tiamulin in the drinking water (2 ml product per litre of water) for 5 days and will provide approximately the following daily dosage of tiamulin depending on the age of the bird:
1 week old poult: 70 mg/kg bodyweight
4 week old poult: 50 mg/kg bodyweight
8 week old poult: 20 – 30 mg/kg bodyweight
20 week old poult: 25 mg/kg bodyweight
Monitor water intake at frequent intervals during medication.
Fresh solutions of tiamulin-medicated drinking water should be made up each day.

https://web.archive.org/web/2013092....com/products/en/denagard_12sol_poultry.shtml

Denagard
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12.5% Solution (Tiamulin)


Product information on this website is for Non-U.S. residents only and is provided by Novartis Animal Health Inc. for general purposes only. Many veterinary products listed are available upon prescription only, and not all such products may be available in all countries. The product information is not intended to provide complete medical information.SHOULD YOUR ANIMAL HAVE A MEDICAL CONDITION, PROMPTLY SEE YOUR OWN VETERINARIAN. WE DO NOT OFFER PERSONALIZED MEDICAL DIAGNOSIS OR ANIMAL-SPECIFIC TREATMENT ADVICE. You should always obtain complete medical information about your veterinary product prescription (including their beneficial medical uses and possible adverse effects) by discussing the appropriate use of any veterinary product directly with the prescribing veterinarian.
Veterinary professionals may obtain complete medical information from the product's information leaflet. Information on these products may vary by country. Animal owners and veterinarians should check with local medical resources and regulatory authorities for information appropriate to their country. In addition, current regulations in many countries limit (or even prohibit in some instances) the ability of Novartis Animal Health Inc. to provide information and/or to respond directly to questions regarding its prescription products. Novartis Animal Health Inc., however, will respond to inquiries from and provide information to your qualified health care professional in accordance with local regulations.
Premix
45% WSG
12.5% Solution
Product Type
Oral antibiotic intended for preventive and therapeutic use in pigs and poultry.
Description and Composition
DENAGARD 12.5% Solution is an aqueous solution containing 125 mg tiamulin hydrogen fumarate per ml of product. It is used for medication in drinking water.
Properties
Tiamulin is a bacteriostatic agent, belonging to the group of pleuromutilins and acts at the ribosomal level to inhibit bacterial protein synthesis. It has a wide spectrum of activity but is particularly active against Brachyspira, Lawsonia and Mycoplasma species. Tiamulin belongs to a category of antibiotics which is not used in human medicine.
Indications
Treatment and prevention of Mycoplasma infections (enzootic pneumonia, chronic respiratory disease), pleuropneumonia and porcine respiratory disease complex.
Denagard is particularly indicated for the treatment of swine dysentery (B.hyodysenteriae)
Dosage and Administration
Pigs:

  • Treatment of swine dysentery: 8.8 mg tiamulin hydrogen fumarate / kg bodyweight (equivalent to 10 ml DENAGARD 12.5% Solution per 142 kg bodyweight; inclusion level 0.006% tiamulin) for 3-5 consecutive days
  • Treatment of PRDC (porcine respiratory disease complex): 15 – 20 mg tiamulin hydrogen fumarate / kg bodyweight (inclusion level 0.012% - 0.018% tiamulin) for 5 – 10 consecutive days
  • Treatment of pleuropneumonia: 20 mg tiamulin hydrogen fumarate / kg bodyweight (inclusion level 0.018% tiamulin) for 5 consecutive days
Indications

Tiamulin (concentration in water in %)

Product
(in ml)

Water
(in liters)

Treatment
(in days)
Treatment swine dysentery

0.006

1

2.1

5
Treatment PRDC

0.012 / 0.018

1

1.0 / 0.7

5 - 10
Treatment pleuropneumonia

0.018

1

0.7

5
Chickens:
  • Prevention of chronic respiratory disease (CRD) and air sacculitis: 12.5 mg tiamulin hydrogen fumarate / kg bodyweight
  • Treatment of chronic respiratory disease (CRD) and air sacculitis: 25 mg tiamulin hydrogen fumarate / kg bodyweight
Turkeys:
  • Prevention of infectious sinusitis and air sacculitis: 12.5 mg tiamulin hydrogen fumarate / kg bodyweight
  • Treatment of infectious sinusitis and air sacculitis: 25 mg tiamulin hydrogen fumarate / kg bodyweight

Indications

Tiamulin (concentration in water in %)

Product
(in ml)

Water
(in liters)

Treatment
(in days)
Prevention CRD / air sacculitis / infectious sinusitis

0.0125

1

1

3 days (1stweek of life); 1-2 days every 3-4 weeks
Treatment CRD / air sacculitis / infectious sinusitis

0.025

2

1

3 – 5
Withdrawal Periods
Withdrawal periods according to national registrations.
Special Precautions and Warnings
Do not administer ionophore anticoccidials (salinomycin, monensin, narasin) to pigs and poultry receiving therapeutic doses of DENAGARD. Pigs and poultry should not receive products containing ionophores during or for at least seven days before or after treatment with DENAGARD.
Formulations and Packages
DENAGARD 12.5% Solution
  • 1 litre dispensing packs
 
Last edited:

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