Manufactured in Florida and takes 3-5 bussiness days to reach anywhere in the United States.
Worms...AGAIN. Please help...I dont know what I can use now!
- Thread starter roz
- Start date
Can you back that statement up with any labs tests or endorsement from a veterinarian?
-Kathy
I think I can dig something up
Dr. Jerry Vanneck
Droncit (praziquantel) kills tapeworms.
Drontal (praziquantel and pyrantel) kills tapeworms, ascarids ("round" worms), and hook worms.
Drontal Plus (praziquantel, pyrantel, and fenbendazole) kills tapeworms, ascarids ("round" worms), hook worms, and whip worms.
It's all marketing strategies.
More basics:
If you give only a benzimidazole (fenbendazole, febantel, etc.), like Panacur, it will kill whip worms in one day, but hook worms and ascarids take three days of treatments. So, if you treat with Panacur, you have to give it three days in a row, unless you are absolutely, positively positive that you're only treating whip worms.
Pyrantel, like Strongid and Nemex, kills only hooks and ascarids in one day, so you only have to give it once. It does not kill whips.
So, by combining pyrantel (in Drontal) with fenbendazole (in Drontal Plus) you only have to treat once, not three days in a row, because the pyrantel kills the hooks and rounds in one day and the fenbendazole kills the whips in one day. (The praziquantel kills the tapes in one day in all three products, regardless.)
Now things get confusing, but fascinating:
Drontal Plus is a great marketing tool designed to keep the dewormer competitive by being "broad spectrum."
Drontal (praziquantal and pyrantel) was the upgrade of simple Droncit (praziquantel only) years ago to compete with Vercom Paste, which was the first major "broad-spoectrum" anthelmintic. Vercom contained praziquantal (tapes) and febantel (ascarids, hooks, and whips). Febantel gets turned into fenbendazole and oxfendazole by the liver.
The problem with Vercom Paste was that you still had to give it three days in a row, like Panacur, to kill the ascarids and rounds. But, it got ALL the tapes, not just the mammallian tapes (Taenia) that Panacur got. (Panacur doesn't kill flea tapeworms).
Vercom was broader spectrum than either Droncit or Panacur, but it still had to be given three days in a row (and it tasted just awful -- cats would get mad as hell when treated, especially by day three!!)
So Droncit, by adding pyrantel, could be marketed as a one-day dewormer that killed all types of tapes, plus ascarids and rounds. Unfortunately, it didn't kill whips. Panacur and Vercom did (but had to be given over three days). The world was not yet perfect.
So Drontal added in fenbendazole initially (instead of febantel, I suppose because of patent laws held by Vercom?). It was called Drontal Plus. Ingenious marketing. Now you could give one pill just one day for tapes, ascarids, rounds, and whips! They nailed the broad spectrum market and blasted the three-day-in-a-row Vercom Paste and Panacur.
Things get even murkier (God bless American free enterprise):
Febantel must not be protected any longer because now Drontal Plus uses it instead of fenbendazole. In addition, pyrantel tartrate is absorbed by the intestines faster than pyrantel pamoate, so many products that used to include the p-pamoate now use p-tartrate.
It gets better:
Even newer is pyrantel emboate, which apparently requires half the dose of the pamoate. AND, Oxantel pamoate got invented, to kill human whip worms, even though its close cousins pyrantel pamoate and p-tartrate don't. Now oxantel is used for canine whips, as well.
These advances have allowed other companies to capitalize on the "broad spectrum" market. Now you can find an "allwormer" with praziquantel, pyrantel emboate, febantel, and/or oxantel, all mixed up in some combination and licensed for tapes, ascarids, hooks, and whips, and all in a one-day treatment.
I suspect Drontal Plus still uses the pyrantel emboate AND good old febantel because it works as well or better than oxantel, OR because they can't get the license because of patent infringment. That may change when the patent expires.
Therefore, I would use either the Drontal Plus, with febantel, or the Allwormer, with the oxantel at this time because I can't find the actual published studies reporting the laboratory effectiveness of febantel against oxantel for whips. Otherwise, the products are the same, in that praziquantel is praziquantel and pyrantel is pyrantel, even though the latter can be absorbed at different rates depending on which analog is used (pamoate, tartrate, emboate). So, read the label.
Oh yes, it gets even better!! Now there's Drontal for Puppies! This product doesn't include praziquantel because of the life cycle of tapeworms -- young puppies can't develop them to adulthood that fast. Drontal for puppies is actually Drontal Plus without the praziquantel (Drontal Minus?? - naw, bad marketing). It contains only febantel and pyrantel embonate for ascarids, hooks, and whips.
With Drontal for Puppies, then, you can treat the same way as if you were using Strongid, except you also are killing whips. However, whips are not a problem in very young puppies. Strongid is good enough.
Broad-spectrum marketing doesn't end here. Heartguard Plus, Interceptor, Sentinel, and Revolution, all employ some facet of the "kill 'em all" anthelmintic strategy now.
Ah, commerce and industry! One spends the first half of one's veterinary career trying to figure out how a product works and the last half trying to figure out why products get invented in the first place.
Oh yes, money.
Print this out, study it, memorize it, then impress your local veterinarian!!
Edited by Staff
Droncit (praziquantel) kills tapeworms.
Drontal (praziquantel and pyrantel) kills tapeworms, ascarids ("round" worms), and hook worms.
Drontal Plus (praziquantel, pyrantel, and fenbendazole) kills tapeworms, ascarids ("round" worms), hook worms, and whip worms.
It's all marketing strategies.
More basics:
If you give only a benzimidazole (fenbendazole, febantel, etc.), like Panacur, it will kill whip worms in one day, but hook worms and ascarids take three days of treatments. So, if you treat with Panacur, you have to give it three days in a row, unless you are absolutely, positively positive that you're only treating whip worms.
Pyrantel, like Strongid and Nemex, kills only hooks and ascarids in one day, so you only have to give it once. It does not kill whips.
So, by combining pyrantel (in Drontal) with fenbendazole (in Drontal Plus) you only have to treat once, not three days in a row, because the pyrantel kills the hooks and rounds in one day and the fenbendazole kills the whips in one day. (The praziquantel kills the tapes in one day in all three products, regardless.)
Now things get confusing, but fascinating:
Drontal Plus is a great marketing tool designed to keep the dewormer competitive by being "broad spectrum."
Drontal (praziquantal and pyrantel) was the upgrade of simple Droncit (praziquantel only) years ago to compete with Vercom Paste, which was the first major "broad-spoectrum" anthelmintic. Vercom contained praziquantal (tapes) and febantel (ascarids, hooks, and whips). Febantel gets turned into fenbendazole and oxfendazole by the liver.
The problem with Vercom Paste was that you still had to give it three days in a row, like Panacur, to kill the ascarids and rounds. But, it got ALL the tapes, not just the mammallian tapes (Taenia) that Panacur got. (Panacur doesn't kill flea tapeworms).
Vercom was broader spectrum than either Droncit or Panacur, but it still had to be given three days in a row (and it tasted just awful -- cats would get mad as hell when treated, especially by day three!!)
So Droncit, by adding pyrantel, could be marketed as a one-day dewormer that killed all types of tapes, plus ascarids and rounds. Unfortunately, it didn't kill whips. Panacur and Vercom did (but had to be given over three days). The world was not yet perfect.
So Drontal added in fenbendazole initially (instead of febantel, I suppose because of patent laws held by Vercom?). It was called Drontal Plus. Ingenious marketing. Now you could give one pill just one day for tapes, ascarids, rounds, and whips! They nailed the broad spectrum market and blasted the three-day-in-a-row Vercom Paste and Panacur.
Things get even murkier (God bless American free enterprise):
Febantel must not be protected any longer because now Drontal Plus uses it instead of fenbendazole. In addition, pyrantel tartrate is absorbed by the intestines faster than pyrantel pamoate, so many products that used to include the p-pamoate now use p-tartrate.
It gets better:
Even newer is pyrantel emboate, which apparently requires half the dose of the pamoate. AND, Oxantel pamoate got invented, to kill human whip worms, even though its close cousins pyrantel pamoate and p-tartrate don't. Now oxantel is used for canine whips, as well.
These advances have allowed other companies to capitalize on the "broad spectrum" market. Now you can find an "allwormer" with praziquantel, pyrantel emboate, febantel, and/or oxantel, all mixed up in some combination and licensed for tapes, ascarids, hooks, and whips, and all in a one-day treatment.
I suspect Drontal Plus still uses the pyrantel emboate AND good old febantel because it works as well or better than oxantel, OR because they can't get the license because of patent infringment. That may change when the patent expires.
Therefore, I would use either the Drontal Plus, with febantel, or the Allwormer, with the oxantel at this time because I can't find the actual published studies reporting the laboratory effectiveness of febantel against oxantel for whips. Otherwise, the products are the same, in that praziquantel is praziquantel and pyrantel is pyrantel, even though the latter can be absorbed at different rates depending on which analog is used (pamoate, tartrate, emboate). So, read the label.
Oh yes, it gets even better!! Now there's Drontal for Puppies! This product doesn't include praziquantel because of the life cycle of tapeworms -- young puppies can't develop them to adulthood that fast. Drontal for puppies is actually Drontal Plus without the praziquantel (Drontal Minus?? - naw, bad marketing). It contains only febantel and pyrantel embonate for ascarids, hooks, and whips.
With Drontal for Puppies, then, you can treat the same way as if you were using Strongid, except you also are killing whips. However, whips are not a problem in very young puppies. Strongid is good enough.
Broad-spectrum marketing doesn't end here. Heartguard Plus, Interceptor, Sentinel, and Revolution, all employ some facet of the "kill 'em all" anthelmintic strategy now.
Ah, commerce and industry! One spends the first half of one's veterinary career trying to figure out how a product works and the last half trying to figure out why products get invented in the first place.
Oh yes, money.
Print this out, study it, memorize it, then impress your local veterinarian!!
Edited by Staff
Last edited by a moderator:
So that's a copy and paste from here:
http://www.sleddogcentral.com/forum/pop_printer_friendly.asp?TOPIC_ID=5189
-Kathy
http://www.sleddogcentral.com/forum/pop_printer_friendly.asp?TOPIC_ID=5189
-Kathy
Last edited:
@BobDBirdDog , I found a source for the chart you posted:
http://www.drsfostersmith.com/pic/article.cfm?aid=1086
-Kathy
http://www.drsfostersmith.com/pic/article.cfm?aid=1086
-Kathy
Oh lord, what have I started. I did not see that hornets nest when I kicked the football. LOL
Thank you Kathy, I forgot where I got it from. I will take your link and edit the post for cited reference. Copyright exempt under fair use and public access and all the other disclaimers. LOL
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