I am battling this in my EE, as well. For whatever reason, pea combs seem to really create an ideal environment for favus!
It does look like it. Just put on some disposable gloves and treat at least once a day. Twice a day is recommended. Gently smear the cream right into the crevices of the comb, and take care not to get it in the eyes or in the nostrils. If yours is not a cream, you can take an old sock and cut a little hole for her comb, put it over her head, spray, and remove. Make sure it's a stretched out old sock and nothing tight!
If your EE is too nervous for the sock treatment, you can just carefully shield her nose and eyes with your hands when you spray. This is easier with a helper.
Wash up well with normal bar soap and warm water afterward, as humans CAN get favus depending on the fungal species. There are some studies published that normal bar soaps / castile types work better than antibacterial ones against fungal agents.